Skin science article
Numbuzin No.3 Skin Softening Serum Versus The Ordinary Multi-Peptide + HA Serum
Numbuzin No.3 Skin Softening Serum Versus The Ordinary Multi-Peptide + HA Serum This smoothing serum is formulated around Bifida Ferment Lysate and Galactomyces Ferment Filtrate to refine skin texture and strengthen the skin barrier. This anti-aging serum is f
Numbuzin No.3 Skin Softening Serum Versus The Ordinary Multi-Peptide + HA Serum
This smoothing serum is formulated around Bifida Ferment Lysate and Galactomyces Ferment Filtrate to refine skin texture and strengthen the skin barrier.
This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Bifida Ferment Lysate
Galactomyces Ferment Filtrate
Butylene Glycol
Methyl Gluceth-20
Water
Niacinamide
PEG-90
1,2-Hexanediol
Glycerin
Squalane
Alteromonas Ferment Extract
Silk Extract
Goat Milk Extract
Sodium Hyaluronate
Panthenol
Adenosine
Glycereth-26
Xanthan Gum
Polyglyceryl-3 Distearate
Glyceryl Stearate Se
Glyceryl Stearate Citrate
Polyglyceryl-3 Methylglucose Distearate
Carbomer
Tromethamine
Caprylyl Glycol
Tropolone
Disodium EDTA
Bifida Ferment Lysate, Galactomyces Ferment Filtrate, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, PEG-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Ferment Extract, Silk Extract, Goat Milk Extract, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Caprylyl Glycol, Tropolone, Disodium EDTA
Lactococcus Ferment Lysate
Acetyl Hexapeptide-8
Pentapeptide-18
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-38
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Acetylarginyltryptophyl Diphenylglycine
Sodium Hyaluronate Crosspolymer
Allantoin
Glycine
Alanine
Serine
Valine
Isoleucine
Proline
Threonine
Histidine
Phenylalanine
Arginine
Aspartic Acid
Trehalose
Fructose
Glucose
Maltose
Urea
Sodium PCA
PCA
Sodium Lactate
Citric Acid
Hydroxypropyl Cyclodextrin
Sodium Chloride
Sodium Hydroxide
Pentylene Glycol
Acacia Senegal Gum
Polysorbate 20
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Trisodium Ethylenediamine Disuccinate
Ethoxydiglycol
Sodium Benzoate
Ethylhexylglycerin
Phenoxyethanol
Chlorphenesin
Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.