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Numbuzin No.9 Secret Firming Serum Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex

Numbuzin No.9 Secret Firming Serum Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles. This anti-aging serum is formulated around Pen

By Peptide Skincare & Beauty Editorial TeamPublished

Numbuzin No.9 Secret Firming Serum Versus Skin Functional Peptides + Cu Complex Anti-Ageing Complex

This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles.

This anti-aging serum is formulated around Pentapeptide-18 and Acetyl Hexapeptide-8 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Hydrogenated Poly(C6-14 Olefin)

Propanediol

Pentaerythrityl Tetraethylhexanoate

Niacinamide

Dimethicone

Butylene Glycol

Butyrospermum Parkii Butter

Hydrogenated Vegetable Oil

Hydroxypropyltrimonium Hyaluronate

Hydrolyzed Hyaluronic Acid

Palmitoyl Tripeptide-5

Acetyl Hexapeptide-8

Lavandula Angustifolia Oil

Citrus Aurantium Dulcis Peel Oil

Rosmarinus Officinalis Leaf Oil

Cedrus Atlantica Bark Oil

Adenosine

Glyceryl Stearate Citrate

Polyglyceryl-3 Methylglucose Distearate

Glyceryl Stearate

Cetearyl Alcohol

Palmitic Acid

Stearic Acid

Dimethicone/Vinyl Dimethicone Crosspolymer

Glyceryl Caprylate

Sodium Polyacrylate

Xanthan Gum

Caprylyl Glycol

1,2-Hexanediol

Ethylhexylglycerin

Disodium EDTA

Carbomer

Tromethamine

Linalool

Limonene

Water, Glycerin, Hydrogenated Poly(C6-14 Olefin), Propanediol, Pentaerythrityl Tetraethylhexanoate, Niacinamide, Dimethicone, Butylene Glycol, Butyrospermum Parkii Butter, Hydrogenated Vegetable Oil, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Lavandula Angustifolia Oil, Citrus Aurantium Dulcis Peel Oil, Rosmarinus Officinalis Leaf Oil, Cedrus Atlantica Bark Oil, Adenosine, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Glyceryl Stearate, Cetearyl Alcohol, Palmitic Acid, Stearic Acid, Dimethicone/Vinyl Dimethicone Crosspolymer, Glyceryl Caprylate, Sodium Polyacrylate, Xanthan Gum, Caprylyl Glycol, 1,2-Hexanediol, Ethylhexylglycerin, Disodium EDTA, Carbomer, Tromethamine, Linalool, Limonene

Betaine

Pentapeptide-18

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Oligopeptide

Copper Tripeptide-1

Glycosaminoglycans

Bis-PEG-8 Dimethicone

Palmitoyl Tripeptide-38

Laminaria Japonica Extract

Sodium Hyaluronate Crosspolymer

Polyglutamic Acid

Aminobutyric Acid

Urea

Polyporus Umbellatus Extract

Phenoxyethanol

Water, Butylene Glycol, Betaine, Pentapeptide-18, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Copper Tripeptide-1, Glycosaminoglycans, Propanediol, Bis-PEG-8 Dimethicone, Palmitoyl Tripeptide-38, Laminaria Japonica Extract, Sodium Hyaluronate Crosspolymer, Polyglutamic Acid, Aminobutyric Acid, Urea, Polyporus Umbellatus Extract, Phenoxyethanol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  7. 07It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  8. 08On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  9. 09Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  10. 10You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
  11. 11Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
  12. 12Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
  13. 13Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
  14. 14Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
  15. 15It’s often used to:
  16. 16Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
  17. 17Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  18. 18So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  19. 19You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Source · skinsort.com ⟶
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Comparison edit

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