Skin science article
Odele Rejuvenating Scalp Serum Versus The Ordinary Multi-Peptide Serum for Hair Density
Odele Rejuvenating Scalp Serum Versus The Ordinary Multi-Peptide Serum for Hair Density What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Water Glycerin Polysorbate 20 Rosmarinus Officinalis Leaf Extract Caffeine Pisum Sativum Peptide Al
Odele Rejuvenating Scalp Serum Versus The Ordinary Multi-Peptide Serum for Hair Density
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Polysorbate 20
Rosmarinus Officinalis Leaf Extract
Caffeine
Pisum Sativum Peptide
Aloe Barbadensis Leaf Juice
Zingiber Officinale Root Extract
Mentha Piperita Leaf Extract
Tocopheryl Acetate
Polyquaternium-10
Polyquaternium-81
Propylene Glycol
Tetrasodium Glutamate Diacetate
Ethylhexylglycerin
Phenoxyethanol
Sodium Hydroxide
Citric Acid
Parfum
Water, Glycerin, Polysorbate 20, Rosmarinus Officinalis Leaf Extract, Caffeine, Pisum Sativum Peptide, Aloe Barbadensis Leaf Juice, Zingiber Officinale Root Extract, Mentha Piperita Leaf Extract, Tocopheryl Acetate, Polyquaternium-10, Polyquaternium-81, Propylene Glycol, Tetrasodium Glutamate Diacetate, Ethylhexylglycerin, Phenoxyethanol, Sodium Hydroxide, Citric Acid, Parfum
Propanediol
Butylene Glycol
Biotinoyl Tripeptide-1
Acetyl Tetrapeptide-3
Larix Europaea Wood Extract
Pisum Sativum Extract
Scutellaria Baicalensis Root Extract
Triticum Vulgare Germ Extract
Glycine Soja Germ Extract
Trifolium Pratense Flower Extract
Camellia Sinensis Leaf Extract
Apigenin
Oleanolic Acid
Arginine
Glycine
Calcium Gluconate
Zinc Chloride
Lactic Acid
Gluconolactone
Dextran
Maltodextrin
Hydroxyethylcellulose
Xanthan Gum
Pentylene Glycol
Dimethyl Isosorbide
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Trisodium Ethylenediamine Disuccinate
Sodium Metabisulfite
Sodium Benzoate
Chlorphenesin
Water, Propanediol, Butylene Glycol, Glycerin, Caffeine, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Larix Europaea Wood Extract, Pisum Sativum Extract, Scutellaria Baicalensis Root Extract, Triticum Vulgare Germ Extract, Glycine Soja Germ Extract, Trifolium Pratense Flower Extract, Camellia Sinensis Leaf Extract, Apigenin, Oleanolic Acid, Arginine, Glycine, Calcium Gluconate, Zinc Chloride, Lactic Acid, Gluconolactone, Dextran, Maltodextrin, Hydroxyethylcellulose, Xanthan Gum, Pentylene Glycol, Dimethyl Isosorbide, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Sodium Metabisulfite, Sodium Benzoate, Phenoxyethanol, Chlorphenesin
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Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!