Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Bioderma Pigmentbio Night Renewer

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Bioderma Pigmentbio Night Renewer This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This brightening night moistu

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Bioderma Pigmentbio Night Renewer

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

This brightening night moisturizer is formulated around Ascorbyl Glucoside and Niacinamide to fade the look of dark spots and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Polysorbate 20

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Disodium EDTA

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Propanediol

Squalane

Ascorbyl Glucoside

Dipropylene Glycol

Butylene Glycol

Hdi/Trimethylol Hexyllactone Crosspolymer

Carbomer

Sodium Hydroxide

Pentylene Glycol

Tocopheryl Acetate

C14-22 Alcohols

1,2-Hexanediol

Caprylyl Glycol

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Salicylic Acid

Sodium Citrate

Lysine

Azelaic Acid

C12-20 Alkyl Glucoside

Disodium Phosphate

Mannitol

Xylitol

Andrographis Paniculata Leaf Extract

Rhamnose

Sodium Metabisulfite

Potassium Phosphate

Saccharide Isomerate

Biosaccharide Gum-1

Glycyrrhiza Glabra Root Extract

Glyceryl Caprylate

Sodium Anisate

Sodium Levulinate

Fructooligosaccharides

Hexapeptide-2

Laminaria Ochroleuca Extract

Parfum

Water, Glycerin, Propanediol, Squalane, Ascorbyl Glucoside, Dipropylene Glycol, Niacinamide, Butylene Glycol, Polymethylsilsesquioxane, Hdi/Trimethylol Hexyllactone Crosspolymer, Carbomer, Sodium Hydroxide, Pentylene Glycol, Tocopheryl Acetate, C14-22 Alcohols, 1,2-Hexanediol, Caprylyl Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Salicylic Acid, Sodium Citrate, Lysine, Azelaic Acid, C12-20 Alkyl Glucoside, Disodium Phosphate, Mannitol, Xylitol, Andrographis Paniculata Leaf Extract, Rhamnose, Sodium Metabisulfite, Potassium Phosphate, Saccharide Isomerate, Biosaccharide Gum-1, Glycyrrhiza Glabra Root Extract, Glyceryl Caprylate, Sodium Anisate, Sodium Levulinate, Fructooligosaccharides, Caprylic/Capric Triglyceride, Hexapeptide-2, Laminaria Ochroleuca Extract, Parfum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Polymethylsilsesquioxane is a silicone used as a film forming agent.

When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.

Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.

If you have concerns about using this ingredient, we recommend speaking with a professional.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Dimethicone
  3. 03Glycerin
  4. 04Tapioca Starch
  5. 05Dimethicone Crosspolymer
  6. 06Retinol
  7. 07Retinyl Propionate
  8. 08Niacinamide
  9. 09Palmitoyl Pentapeptide-4
  10. 10Polyacrylamide
  11. 11C13-14 Isoparaffin
  12. 12DMDM Hydantoin
  13. 13Polysorbate 20
  14. 14Laureth-4
  15. 15Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  16. 16Laureth-7
  17. 17Dimethiconol
  18. 18Polymethylsilsesquioxane
  19. 19Aminomethyl Propanol
  20. 20Titanium Dioxide
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side