Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus CeraVe Renewing SA Cleanser

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus CeraVe Renewing SA Cleanser This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This salicylic acid gel cleanser is

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus CeraVe Renewing SA Cleanser

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

This salicylic acid gel cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Polysorbate 20

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Disodium EDTA

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Cocamidopropyl Hydroxysultaine

Sodium Lauroyl Sarcosinate

Gluconolactone

PEG-150 Pentaerythrityl Tetrastearate

Sodium Methyl Cocoyl Taurate

Zea Mays Oil

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Calcium Gluconate

Sodium Chloride

Salicylic Acid

Sodium Benzoate

Sodium Lauroyl Lactylate

Cholecalciferol

Cholesterol

Phenoxyethanol

Tetrasodium EDTA

Hydrolyzed Hyaluronic Acid

Phytosphingosine

Xanthan Gum

Ethylhexylglycerin

Water, Cocamidopropyl Hydroxysultaine, Glycerin, Sodium Lauroyl Sarcosinate, Niacinamide, Gluconolactone, PEG-150 Pentaerythrityl Tetrastearate, Sodium Methyl Cocoyl Taurate, Zea Mays Oil, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Calcium Gluconate, Sodium Chloride, Salicylic Acid, Sodium Benzoate, Sodium Lauroyl Lactylate, Cholecalciferol, Cholesterol, Phenoxyethanol, Disodium EDTA, Tetrasodium EDTA, Hydrolyzed Hyaluronic Acid, Phytosphingosine, Xanthan Gum, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Dimethicone
  3. 03Glycerin
  4. 04Tapioca Starch
  5. 05Dimethicone Crosspolymer
  6. 06Retinol
  7. 07Retinyl Propionate
  8. 08Niacinamide
  9. 09Palmitoyl Pentapeptide-4
  10. 10Polyacrylamide
  11. 11C13-14 Isoparaffin
  12. 12DMDM Hydantoin
  13. 13Polysorbate 20
  14. 14Laureth-4
  15. 15Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  16. 16Laureth-7
  17. 17Dimethiconol
  18. 18Polymethylsilsesquioxane
  19. 19Aminomethyl Propanol
  20. 20Titanium Dioxide
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side