Skin science article
Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane
Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This barrier-repair mo
Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane
This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.
This barrier-repair moisturizer is formulated around Squalane and Pseudoalteromonas Ferment Extract to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Glycerin
Tapioca Starch
Dimethicone Crosspolymer
Retinol
Retinyl Propionate
Niacinamide
Palmitoyl Pentapeptide-4
Polyacrylamide
C13-14 Isoparaffin
DMDM Hydantoin
Polysorbate 20
Laureth-4
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Laureth-7
Dimethiconol
Polymethylsilsesquioxane
Aminomethyl Propanol
Titanium Dioxide
Disodium EDTA
Iodopropynyl Butylcarbamate
Caprylic/Capric Triglyceride
Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride
Squalane
Bis-PEG-18 Methyl Ether Dimethyl Silane
Sucrose Stearate
Stearyl Alcohol
PEG-8 Stearate
Myristyl Myristate
Prunus Armeniaca Kernel Oil
Phenoxyethanol
Persea Gratissima Oil
Glyceryl Stearate
Cetyl Alcohol
Oryza Sativa Bran Oil
Olea Europaea Fruit Oil
Chlorphenesin
Stearic Acid
Palmitic Acid
Carbomer
Trisodium Ethylenediamine Disuccinate
Prunus Amygdalus Dulcis Oil
Xanthan Gum
Ethylhexylglycerin
Sodium Hydroxide
Tocopherol
Glycine Soja Oil
Pseudoalteromonas Ferment Extract
Myristic Acid
Hydroxypalmitoyl Sphinganine
Salicylic Acid
Helianthus Annuus Seed Oil
Rosmarinus Officinalis Leaf Extract
Citric Acid
Water, Glycerin, Dimethicone, Squalane, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sucrose Stearate, Stearyl Alcohol, PEG-8 Stearate, Myristyl Myristate, Prunus Armeniaca Kernel Oil, Phenoxyethanol, Persea Gratissima Oil, Glyceryl Stearate, Cetyl Alcohol, Oryza Sativa Bran Oil, Olea Europaea Fruit Oil, Chlorphenesin, Stearic Acid, Palmitic Acid, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trisodium Ethylenediamine Disuccinate, Prunus Amygdalus Dulcis Oil, Xanthan Gum, Ethylhexylglycerin, Sodium Hydroxide, Tocopherol, Glycine Soja Oil, Pseudoalteromonas Ferment Extract, Myristic Acid, Hydroxypalmitoyl Sphinganine, Salicylic Acid, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Citric Acid
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!