Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Lancôme Renergie Multi-lift Ultra Full Spectrum Anti-ageing Cream

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Lancôme Renergie Multi-lift Ultra Full Spectrum Anti-ageing Cream

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

This anti-aging treatment is formulated around 3-O-Ethyl Ascorbic Acid and Adenosine to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Polysorbate 20

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Disodium EDTA

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Butyrospermum Parkii Butter

Octyldodecanol

Butylene Glycol

Cetyl Alcohol

PEG-100 Stearate

Glyceryl Stearate

3-O-Ethyl Ascorbic Acid

Tocopheryl Acetate

Guanosine

Cyathea Medullaris Leaf Extract

Vaccinium Myrtillus Fruit Extract

Saccharum Officinarum Extract

Hydroxypropyl Tetrahydropyrantriol

Sodium Citrate

Hydrolyzed Linseed Extract

Hydrolyzed Lupine Protein

Sodium Benzoate

Sodium Levulinate

Stearic Acid

Phenoxyethanol

Phenylethyl Resorcinol

Adenosine

Acer Saccharum Extract

Palmitic Acid

Chlorphenesin

Poloxamer 338

Limonene

Xanthan Gum

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Benzyl Alcohol

Cinnamic Acid

Propylene Glycol

2-Oleamido-1,3-Octadecanediol

Leontopodium Alpinum Extract

Biosaccharide Gum-1

Alpha-Isomethyl Ionone

Myristic Acid

Geraniol

Citric Acid

Potassium Hydroxide

Citrus Aurantium Dulcis Fruit Extract

Citrus Limon Fruit Extract

Potassium Sorbate

BHT

Levulinic Acid

Hexyl Cinnamal

Glyceryl Caprylate

Parfum

Water, Glycerin, Dimethicone, Butyrospermum Parkii Butter, Octyldodecanol, Butylene Glycol, Cetyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, 3-O-Ethyl Ascorbic Acid, Tocopheryl Acetate, C13-14 Isoparaffin, Guanosine, Cyathea Medullaris Leaf Extract, Vaccinium Myrtillus Fruit Extract, Saccharum Officinarum Extract, Hydroxypropyl Tetrahydropyrantriol, Sodium Citrate, Hydrolyzed Linseed Extract, Hydrolyzed Lupine Protein, Sodium Benzoate, Sodium Levulinate, Stearic Acid, Phenoxyethanol, Phenylethyl Resorcinol, Adenosine, Acer Saccharum Extract, Palmitic Acid, Polyacrylamide, Chlorphenesin, Poloxamer 338, Limonene, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Benzyl Alcohol, Cinnamic Acid, Propylene Glycol, 2-Oleamido-1,3-Octadecanediol, Leontopodium Alpinum Extract, Biosaccharide Gum-1, Alpha-Isomethyl Ionone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Myristic Acid, Geraniol, Disodium EDTA, Citric Acid, Potassium Hydroxide, Citrus Aurantium Dulcis Fruit Extract, Citrus Limon Fruit Extract, Potassium Sorbate, BHT, Laureth-7, Levulinic Acid, Hexyl Cinnamal, Glyceryl Caprylate, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue.

This ingredient has been found to be non-sensitizing and safe for use in cosmetics.

Two things floating around online that cause fear-mongering:

There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk.

The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety.

One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

This ingredient is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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