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Skin science article

Olehenriksen Strength Trainer Peptide Boost Moisturizer Versus La Roche-Posay Toleriane Double Repair Face Moisturizer

Olehenriksen Strength Trainer Peptide Boost Moisturizer Versus La Roche-Posay Toleriane Double Repair Face Moisturizer This barrier-repair moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to strengthen the skin barrier and soften the look

Olehenriksen Strength Trainer Peptide Boost Moisturizer Versus La Roche-Posay Toleriane Double Repair Face Moisturizer

This barrier-repair moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to strengthen the skin barrier and soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Dicaprylyl Carbonate

Glycerin

Methylpropanediol

Cetearyl Alcohol

Stearyl Alcohol

Mangifera Indica Seed Butter

Niacinamide

Acetyl Hexapeptide-1

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Acetyl Tetrapeptide-2

Acetyl Dipeptide-1 Cetyl Ester

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Carnosine

Ceramide NP

Ceramide AP

Ceramide EOP

Collagen

Serine

Alanine

Glycine

Glutamic Acid

Lysine Hcl

Threonine

Arginine

Proline

Hyaluronic Acid

Sodium Hyaluronate

Linoleic Acid

Linolenic Acid

Sodium PCA

Sodium Lactate

Panthenol

Tocopherol

Tocopheryl Acetate

Betaine

PCA

Cyanocobalamin

Xylitol

Anhydroxylitol

Xylitylglucoside

Sorbitan Olivate

Carbomer

Hydroxyethylcellulose

Xanthan Gum

Cetearyl Olivate

Sorbitan Laurate

Phytosphingosine

Cholesterol

Polysorbate 60

Butylene Glycol

Hydroxyacetophenone

Glycine Soja Oil

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polysorbate 20

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Dimethicone

Sodium Phytate

Sodium Lauroyl Lactylate

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Leuconostoc/Radish Root Ferment Filtrate

Citric Acid

Caprylyl Glycol

Ethylhexylglycerin

Phenoxyethanol

Parfum

Citral

Limonene

Linalool

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Methylpropanediol, Cetearyl Alcohol, Stearyl Alcohol, Mangifera Indica Seed Butter, Niacinamide, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carnosine, Ceramide NP, Ceramide AP, Ceramide EOP, Collagen, Serine, Alanine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Hyaluronic Acid, Sodium Hyaluronate, Linoleic Acid, Linolenic Acid, Sodium PCA, Sodium Lactate, Panthenol, Tocopherol, Tocopheryl Acetate, Betaine, PCA, Cyanocobalamin, Xylitol, Anhydroxylitol, Xylitylglucoside, Sorbitan Olivate, Carbomer, Hydroxyethylcellulose, Xanthan Gum, Cetearyl Olivate, Sorbitan Laurate, Phytosphingosine, Cholesterol, Polysorbate 60, Butylene Glycol, Hydroxyacetophenone, Glycine Soja Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Dimethicone, Sodium Phytate, Sodium Lauroyl Lactylate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Parfum, Citral, Limonene, Linalool

Squalane

Zea Mays Starch

Ammonium Polyacryloyldimethyl Taurate

Myristyl Myristate

Stearic Acid

Potassium Cetyl Phosphate

Glyceryl Stearate Se

Sodium Hydroxide

Myristic Acid

Palmitic Acid

Capryloyl Glycine

Water, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03This peptide is a lab-made "messenger peptide" that differs from other peptides; it's mostly known for nudging skin pigmentation upward rather than smoothing wrinkles like other peptides.
  4. 04It works by mimicing parts of the alpha-melanocyte-stimulating hormone signaling pathway by telling pigment making cells (melanocytes) to make more melanin.
  5. 05Our bodies produce melanin in response to UV so this peptide is marketed for supporting tanning and has also been explored in hypopigmentation contexts like vitiligo.
  6. 06Though there is some human data, it's doesn't have the best "single-ingredient" evidence.
  7. 07For example, an 8 week clinical study in middle-aged Chinese women found using an essence with 0.02% acetyl hexapeptide-1 + retinol improved photoaging related measures. Since it was a combo product, you can't attribute the results to the peptide alone.
  8. 08In vitiligo research a topical cream with acetyl hexapeptide-1 plus other actives was reported to support repigmentation in some areas. Again, this was a combo product so it's not a pure “acetyl hexapeptide-1 did this” conclusion.
  9. 09If you're trying to fade hyperpigmentation like melasma and sun spots, this may not be the ingredient for you. Again, its generally positioned as a pro-pigment / tanning support peptide.
  10. 10Peptides are usually well tolerated but be sure to patch test if you're cautious or have extra sensitive skin.
  11. 11Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
  12. 12As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
  13. 13It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
  14. 14A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
  15. 15Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
  16. 16Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
  17. 17Some studies suggest betaine may support making skin tone more even.
  18. 18Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
  19. 19Betaine is also known as trimethylglycine.
  20. 20Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Source · skinsort.com
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Product index

Related product references

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Comparison edit

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