OneSkin: Topical Products for Healthy Aging

Engineered to reverse skin’s visible biological age1.

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

The real proof? It’s in the numbers.

10+

Years of Research

900+

Peptides Screened

22+

Patents & Publications

15000+

5-Star Reviews

OUR APPROACH

Led by science, not hype.

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Ongoing clinical studies

Conducted by independent, third-party research organizations.

Peer-reviewed publications

The gold standard for scientific research and in skincare.

Citations

1. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)
2. Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
3. Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
4. Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
5. Zonari, A., et al. OS-01 Peptide Topical Formulation Improves Skin Barrier Function and Reduces Systemic Inflammation Markers: A Pilot 12-Week Clinical Trial. J Cosmet Dermatol. 2025; 24: e70169. doi: 10.1111/jocd.70169