Skin science article
Pacifica Dreamy Youth Super Peptide Cream Versus Charlotte Tilbury Magic Cream Moisturizer
Pacifica Dreamy Youth Super Peptide Cream Versus Charlotte Tilbury Magic Cream Moisturizer This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-5 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles. This an
Pacifica Dreamy Youth Super Peptide Cream Versus Charlotte Tilbury Magic Cream Moisturizer
This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-5 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.
This anti-aging moisturizer is formulated around Butyrospermum Parkii Butter and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Helianthus Annuus Seed Oil
Myristyl Myristate
Isopropyl Myristate
C12-15 Alkyl Benzoate
Butyrospermum Parkii Butter
Stearic Acid
Glyceryl Stearate Citrate
Glycerin
Palmitoyl Tripeptide-5
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Propanediol
Glyceryl Stearate
Sodium Stearoyl Glutamate
Cetyl Alcohol
Stearyl Alcohol
Betaine
Arginine
Sodium PCA
Hibiscus Sabdariffa Flower Extract
Iris Pallida Leaf Cell Extract
Rosa Damascena Flower Water
Pelargonium Graveolens Oil
Dibutyl Lauroyl Glutamide
Tocopheryl Acetate
Xanthan Gum
Phenoxyethanol
Ethylhexylglycerin
Water, Helianthus Annuus Seed Oil, Myristyl Myristate, Isopropyl Myristate, C12-15 Alkyl Benzoate, Butyrospermum Parkii Butter, Stearic Acid, Glyceryl Stearate Citrate, Glycerin, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Propanediol, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Stearyl Alcohol, Betaine, Arginine, Sodium PCA, Hibiscus Sabdariffa Flower Extract, Iris Pallida Leaf Cell Extract, Rosa Damascena Flower Water, Pelargonium Graveolens Oil, Dibutyl Lauroyl Glutamide, Tocopheryl Acetate, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin
Glyceryl Stearate Se
Butylene Glycol
Isononyl Isononanoate
Caprylic/Capric Triglyceride
Ethylhexyl Palmitate
Cyclopentasiloxane
Dimethicone
Polyester-7
Neopentyl Glycol Diheptanoate
Hydrogenated Rapeseed Oil
Steareth-21
Avena Sativa Kernel Extract
Carbomer
Dimethiconol
Potassium Cetyl Phosphate
Chlorphenesin
Caprylyl Glycol
Hydrolyzed Viola Tricolor Extract
Allantoin
Aloe Barbadensis Leaf Juice Powder
Disodium EDTA
Camellia Oleifera Seed Oil
Rosa Canina Fruit Oil
Rosa Damascena Extract
Sodium Hydroxide
Michelia Alba Leaf Oil
Sodium Lactate
PEG-8
Coco-Glucoside
Sodium Hyaluronate
Tocopherol
Ascorbyl Palmitate
Plumeria Rubra Flower Extract
Ascorbic Acid
Citric Acid
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Hydrolyzed Vegetable Protein
Citronellol
Geraniol
Linalool
Water, C12-15 Alkyl Benzoate, Glyceryl Stearate Se, Butylene Glycol, Glycerin, Isononyl Isononanoate, Caprylic/Capric Triglyceride, Cetyl Alcohol, Ethylhexyl Palmitate, Cyclopentasiloxane, Dimethicone, Polyester-7, Phenoxyethanol, Neopentyl Glycol Diheptanoate, Hydrogenated Rapeseed Oil, Butyrospermum Parkii Butter, Steareth-21, Avena Sativa Kernel Extract, Carbomer, Dimethiconol, Potassium Cetyl Phosphate, Chlorphenesin, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Viola Tricolor Extract, Allantoin, Aloe Barbadensis Leaf Juice Powder, Disodium EDTA, Tocopheryl Acetate, Camellia Oleifera Seed Oil, Rosa Canina Fruit Oil, Rosa Damascena Extract, Sodium Hydroxide, Helianthus Annuus Seed Oil, Michelia Alba Leaf Oil, Sodium Lactate, PEG-8, Ethylhexylglycerin, Coco-Glucoside, Sodium Hyaluronate, Tocopherol, Ascorbyl Palmitate, Plumeria Rubra Flower Extract, Ascorbic Acid, Citric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Vegetable Protein, Citronellol, Geraniol, Linalool
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
C12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long.
In cosmetics, it plays several roles:
The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility.
This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product.
It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own.
Overall, this ingredient is well tolerated.
This ingredient is fungal acne safe because it is an ester of benzoic acid.
Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food.
Benzoic acid is actually used as a preservative to stop yeast from growing.
The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well).
In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond.
So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.