Skin science article
Paula's Choice 1% Retinol Treatment Versus Carrot & Stick The Repair Serum
Paula's Choice 1% Retinol Treatment Versus Carrot & Stick The Repair Serum This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. This barrier-repair serum is formulated arou
Paula's Choice 1% Retinol Treatment Versus Carrot & Stick The Repair Serum
This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.
This barrier-repair serum is formulated around Niacinamide and Sh-Oligopeptide-1 to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Dimethicone
Glycerin
Butylene Glycol
Isononyl Isononanoate
Castor Isostearate Succinate
Glyceryl Stearate
C12-15 Alkyl Benzoate
Dimethicone Crosspolymer
PEG-33
Polysorbate 20
Behenyl Alcohol
PEG-100 Stearate
Pentaerythrityl Tetraisostearate
Polymethylsilsesquioxane
Tetrahexyldecyl Ascorbate
Retinol
Ceramide Ng
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Dipotassium Glycyrrhizate
Glycyrrhiza Glabra Root Extract
Avena Sativa Kernel Extract
Arctium Lappa Seed Oil
Salix Alba Extract
Glycine Soja Sterols
Lecithin
Allantoin
Tocopheryl Acetate
Hydrolyzed Soy Protein
Sorbitan Laurate
Acetyl Dipeptide-1 Cetyl Ester
Disodium EDTA
Hydroxyethylcellulose
Palmitoyl Tripeptide-1
Sodium Hydroxide
Tribehenin
Caprylyl Glycol
Ethylhexylglycerin
Pentylene Glycol
PEG-75 Shea Butter Glycerides
PPG-12/Smdi Copolymer
PEG-10 Phytosterol
PEG-8 Dimethicone
PEG-14
Magnesium Aluminum Silicate
Arachidyl Glucoside
Arachidyl Alcohol
Sclerotium Gum
Carbomer
Phenoxyethanol
Benzoic Acid
Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid
Niacinamide
Acacia Senegal Gum
Hydrolyzed Rhizobian Gum
Camellia Sinensis Leaf Extract
Chamomilla Recutita Flower Extract
PCA
Sodium PCA
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-11
Sh-Polypeptide-9
Acetyl Hexapeptide-8
Arginine
Aspartic Acid
Acetyl Glutamine
Carnitine
Alanine
Glycine
Histidine
Isoleucine
Phenylalanine
Proline
Serine
Threonine
Valine
Caffeine
Ruscus Aculeatus Root Extract
Chenopodium Quinoa Seed Extract
Bacillus
Citrus Reticulata Peel Extract
Codonopsis Lanceolata Extract
Coix Lacryma-Jobi Ma-Yuen Seed Extract
Chrysanthemum Parthenium Extract
Digitaria Ciliaris Flower Extract
Nelumbo Nucifera Seed Extract
Paeonia Suffruticosa Root Extract
Paeonia Albiflora Flower Extract
Polygonum Odoratum Extract
Sodium Lactate
Polyglutamic Acid
Xanthan Gum
1,2-Hexanediol
Citric Acid
Sodium Benzoate
Sodium Levulinate
Potassium Sorbate
Water, Niacinamide, Glycerin, Acacia Senegal Gum, Hydrolyzed Rhizobian Gum, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, PCA, Sodium PCA, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Sodium Hyaluronate, Acetyl Hexapeptide-8, Arginine, Aspartic Acid, Acetyl Glutamine, Lecithin, Carnitine, Alanine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Caffeine, Ruscus Aculeatus Root Extract, Chenopodium Quinoa Seed Extract, Bacillus, Citrus Reticulata Peel Extract, Codonopsis Lanceolata Extract, Coix Lacryma-Jobi Ma-Yuen Seed Extract, Chrysanthemum Parthenium Extract, Digitaria Ciliaris Flower Extract, Glycyrrhiza Glabra Root Extract, Nelumbo Nucifera Seed Extract, Paeonia Suffruticosa Root Extract, Paeonia Albiflora Flower Extract, Polygonum Odoratum Extract, Sodium Lactate, Polyglutamic Acid, Xanthan Gum, Butylene Glycol, 1,2-Hexanediol, Citric Acid, Caprylyl Glycol, Sodium Benzoate, Sodium Levulinate, Potassium Sorbate, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!