Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel

Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture. This pore-care moist

Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel

This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture.

This pore-care moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to refine the look of pores and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Niacinamide

Acetyl Glucosamine

Ascorbyl Glucoside

Butylene Glycol

Phospholipids

Sodium Hyaluronate

Allantoin

Boerhavia Diffusa Root Extract

Glycerin

Dipotassium Glycyrrhizate

Glycyrrhiza Glabra Root Extract

Ubiquinone

Epigallocatechin Gallate

Beta-Glucan

Panthenol

Carnosine

Genistein

Citric Acid

Sodium Citrate

Sodium Hydroxide

Xanthan Gum

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

Water, Niacinamide, Acetyl Glucosamine, Ascorbyl Glucoside, Butylene Glycol, Phospholipids, Sodium Hyaluronate, Allantoin, Boerhavia Diffusa Root Extract, Glycerin, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Ubiquinone, Epigallocatechin Gallate, Beta-Glucan, Panthenol, Carnosine, Genistein, Citric Acid, Sodium Citrate, Sodium Hydroxide, Xanthan Gum, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol

Cyclopentasiloxane

Bis-Phenylpropyl Dimethicone

Laminaria Saccharina Extract

Avena Sativa Kernel Extract

Camellia Oleifera Leaf Extract

Vitis Vinifera Seed Extract

Triticum Vulgare Germ Oil

Tocopheryl Acetate

Phenyl Trimethicone

Dimethicone

Tetrahexyldecyl Ascorbate

Superoxide Dismutase

Isohexadecane

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium Carbomer

Dimethicone/Vinyl Dimethicone Crosspolymer

Polysorbate 80

Hydroxyethylcellulose

Water, Cyclopentasiloxane, Butylene Glycol, Glycerin, Bis-Phenylpropyl Dimethicone, Niacinamide, Laminaria Saccharina Extract, Avena Sativa Kernel Extract, Camellia Oleifera Leaf Extract, Vitis Vinifera Seed Extract, Triticum Vulgare Germ Oil, Tocopheryl Acetate, Phenyl Trimethicone, Dimethicone, Dipotassium Glycyrrhizate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Phospholipids, Superoxide Dismutase, Isohexadecane, Panthenol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Carbomer, Dimethicone/Vinyl Dimethicone Crosspolymer, Polysorbate 80, Hydroxyethylcellulose, Ethylhexylglycerin, Phenoxyethanol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Niacinamide
  3. 03Acetyl Glucosamine
  4. 04Ascorbyl Glucoside
  5. 05Butylene Glycol
  6. 06Phospholipids
  7. 07Sodium Hyaluronate
  8. 08Allantoin
  9. 09Boerhavia Diffusa Root Extract
  10. 10Glycerin
  11. 11Dipotassium Glycyrrhizate
  12. 12Glycyrrhiza Glabra Root Extract
  13. 13Ubiquinone
  14. 14Epigallocatechin Gallate
  15. 15Beta-Glucan
  16. 16Panthenol
  17. 17Carnosine
  18. 18Genistein
  19. 19Citric Acid
  20. 20Sodium Citrate
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side