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Skin science article

Paula's Choice Barrier Repair Advanced Moisturizer Versus rhode Barrier Restore Cream

Paula's Choice Barrier Repair Advanced Moisturizer Versus rhode Barrier Restore Cream This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulate

Paula's Choice Barrier Repair Advanced Moisturizer Versus rhode Barrier Restore Cream

This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Niacinamide and Squalane to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

2,3-Butanediol

Dicaprylyl Carbonate

Glycerin

Glyceryl Stearate

Cocoglycerides

Ceramide Ag

Ceramide NP

Hydroxyacetophenone

Sodium Hyaluronate

Ceramide EOP

Ceramide Ng

Ceramide AP

Adenosine

Tocopherol

Butyrospermum Parkii Butter

Palmitoyl Tripeptide-5

Hexylene Glycol

Trehalose

Cholesterol

Squalane

Sodium Phytate

Urea

Hydrogenated Lecithin

Citrullus Lanatus Seed Oil

Caprylyl Glycol

Sodium PCA

Polyquaternium-51

Triacetin

Sodium Polyacrylate

Xanthan Gum

Ethylhexyl Stearate

Phenoxyethanol

Sodium Stearoyl Glutamate

Ethylhexylglycerin

Water, 2,3-Butanediol, Dicaprylyl Carbonate, Glycerin, Glyceryl Stearate, Cocoglycerides, Ceramide Ag, Ceramide NP, Hydroxyacetophenone, Sodium Hyaluronate, Ceramide EOP, Ceramide Ng, Ceramide AP, Adenosine, Tocopherol, Butyrospermum Parkii Butter, Palmitoyl Tripeptide-5, Hexylene Glycol, Trehalose, Cholesterol, Squalane, Sodium Phytate, Urea, Hydrogenated Lecithin, Citrullus Lanatus Seed Oil, Caprylyl Glycol, Sodium PCA, Polyquaternium-51, Triacetin, Sodium Polyacrylate, Xanthan Gum, Ethylhexyl Stearate, Phenoxyethanol, Sodium Stearoyl Glutamate, Ethylhexylglycerin

Caprylic/Capric Triglyceride

Behenyl Alcohol

Xylitylglucoside

Niacinamide

Sodium Acrylates Copolymer

Acetyl Tetrapeptide-2

Palmitoyl Heptapeptide-27

Palmitoyl Oligopeptide-78

Palmitoyl Octapeptide-24

Anhydroxylitol

1,2-Hexanediol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Xylitol

Lecithin

Glucose

Bisabolol

Teprenone

Polysorbate 60

Sorbitan Isostearate

Euterpe Oleracea Fruit Extract

Potassium Sorbate

Citric Acid

Sorbic Acid

Lactic Acid/Glycolic Acid Copolymer

Polyvinyl Alcohol

Sodium Hydroxide

Water, Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, Behenyl Alcohol, Xylitylglucoside, Niacinamide, Squalane, Sodium Acrylates Copolymer, Acetyl Tetrapeptide-2, Palmitoyl Heptapeptide-27, Palmitoyl Oligopeptide-78, Palmitoyl Octapeptide-24, Phenoxyethanol, Anhydroxylitol, 1,2-Hexanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xylitol, Lecithin, Ethylhexylglycerin, Glucose, Bisabolol, Sodium Hyaluronate, Teprenone, Polysorbate 60, Sorbitan Isostearate, Caprylyl Glycol, Euterpe Oleracea Fruit Extract, Potassium Sorbate, Citric Acid, Sorbic Acid, Lactic Acid/Glycolic Acid Copolymer, Tocopherol, Polyvinyl Alcohol, Sodium Hydroxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Butyrospermum Parkii Butter
  3. 03Ceteareth-6 Olivate
  4. 04Butylene Glycol
  5. 05C13-15 Alkane
  6. 06Glycerin
  7. 07Glyceryl Stearate
  8. 08Polyglyceryl-4 Laurate
  9. 09Decyl Oleate
  10. 10Linum Usitatissimum Seed Oil
  11. 11Salvia Hispanica Seed Oil
  12. 12Olea Europaea Fruit Oil
  13. 13Passiflora Edulis Seed Oil
  14. 14Borago Officinalis Seed Oil
  15. 15Hydrogenated Olive Oil
  16. 16Psidium Guajava Fruit Extract
  17. 17Olea Europaea Oil Unsaponifiables
  18. 18Limnanthes Alba Seed Oil
  19. 19Linoleic Acid
  20. 20Linolenic Acid
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice Perfect Cleansing Oil

Paula's Choice Perfect Cleansing Oil Paula's Choice Perfect Cleansing Oil ingredients explained: Caprylic/Capric Triglyceride (Skin-Replenishing), Helianthus Annuus (Sunflower) Seed Oil (No…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side