Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice Clear Oil-Free Moisturizer Versus AMOREPACIFIC The Essential Creme Fluid

Paula's Choice Clear Oil-Free Moisturizer Versus AMOREPACIFIC The Essential Creme Fluid This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness. This hydrating treatment is formulated aro

Paula's Choice Clear Oil-Free Moisturizer Versus AMOREPACIFIC The Essential Creme Fluid

This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness.

This hydrating treatment is formulated around Camellia Sinensis Leaf Extract and Camellia Sinensis Seed Oil to hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Ethyl Macadamiate

Glycerin

Cetearyl Alcohol

Propanediol

Triethylhexanoin

Sodium Acrylates Copolymer

Glyceryl Stearate

PEG-100 Stearate

Glycyrrhiza Glabra Root

Hydrolyzed Pumpkin Seedcake

Vaccinium Angustifolium Fruit Extract

Euterpe Oleracea Fruit Extract

Prunus Serotina Fruit Extract

Niacinamide

Tripeptide-29

Ceramide NP

Ceramide AP

Ceramide EOP

Sodium Hyaluronate

Phytosphingosine

Cholesterol

Panthenol

Sodium PCA

Adenosine

Lecithin

Arginine

Sodium Lauroyl Lactylate

Sodium Gluconate

Citric Acid

Isohexadecane

Xanthan Gum

Carbomer

Phenoxyethanol

Ethylhexylglycerin

Water, Ethyl Macadamiate, Glycerin, Cetearyl Alcohol, Propanediol, Triethylhexanoin, Sodium Acrylates Copolymer, Glyceryl Stearate, PEG-100 Stearate, Glycyrrhiza Glabra Root, Hydrolyzed Pumpkin Seedcake, Vaccinium Angustifolium Fruit Extract, Euterpe Oleracea Fruit Extract, Prunus Serotina Fruit Extract, Niacinamide, Tripeptide-29, Ceramide NP, Ceramide AP, Ceramide EOP, Sodium Hyaluronate, Phytosphingosine, Cholesterol, Panthenol, Sodium PCA, Adenosine, Lecithin, Arginine, Sodium Lauroyl Lactylate, Sodium Gluconate, Citric Acid, Isohexadecane, Xanthan Gum, Carbomer, Phenoxyethanol, Ethylhexylglycerin

Hydrogenated Poly(C6-14 Olefin)

Dimethicone

Stearic Acid

Palmitic Acid

Camellia Sinensis Leaf Extract

Camellia Sinensis Seed Oil

Butylene Glycol

Glyceryl Caprylate

Hydroxypropyl Starch Phosphate

Hydrogenated Lecithin

Caprylic/Capric Triglyceride

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Bis-Diglyceryl Polyacyladipate-2

Caprylyl Glycol

Tocopherol

Disodium EDTA

1,2-Hexanediol

Parfum

Water, Hydrogenated Poly(C6-14 Olefin), Propanediol, Glycerin, Dimethicone, Stearic Acid, Palmitic Acid, Camellia Sinensis Leaf Extract, Camellia Sinensis Seed Oil, Arginine, Butylene Glycol, Glyceryl Stearate, Cetearyl Alcohol, Glyceryl Caprylate, Hydroxypropyl Starch Phosphate, Hydrogenated Lecithin, Caprylic/Capric Triglyceride, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Bis-Diglyceryl Polyacyladipate-2, Caprylyl Glycol, Carbomer, Tocopherol, Disodium EDTA, Ethylhexylglycerin, 1,2-Hexanediol, Parfum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03This ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.
  4. 04It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.
  5. 05Another pro?
  6. 06It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.
  7. 07That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.
  8. 08Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen f…
  9. 09On maximum concentrations:
  10. 10In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older
  11. 11Caprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.
  12. 12Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.
  13. 13Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.
  14. 14Decyl Glucoside is a plant-derived surfactant and emulsion stabilizer. It is created by reacting glucose with the fatty acids from plants.
  15. 15Like all surfactants, it works by lowering the surface tension between water and oil. This makes it so that dirt, sebum, and makeup can be lifted off your skin and rinsed away. It also produces a dense and creamy foam.
  16. 16Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.
  17. 17Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).
  18. 18Typical use levels range from 5-20% in rinse-off cleansers.
  19. 19One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-fr…
  20. 20This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is not within the C11-24 chain length that Malassezia can metabolize.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side