Skin science article
Paula's Choice Clear Oil-Free Moisturizer Versus La Roche-Posay Effaclar Duo+ Global Acne Treatment
Paula's Choice Clear Oil-Free Moisturizer Versus La Roche-Posay Effaclar Duo+ Global Acne Treatment This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness. This acne treatment is formula
Paula's Choice Clear Oil-Free Moisturizer Versus La Roche-Posay Effaclar Duo+ Global Acne Treatment
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness.
This acne treatment is formulated around Niacinamide and Zinc PCA to clear breakouts and balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ethyl Macadamiate
Glycerin
Cetearyl Alcohol
Propanediol
Triethylhexanoin
Sodium Acrylates Copolymer
Glyceryl Stearate
PEG-100 Stearate
Glycyrrhiza Glabra Root
Hydrolyzed Pumpkin Seedcake
Vaccinium Angustifolium Fruit Extract
Euterpe Oleracea Fruit Extract
Prunus Serotina Fruit Extract
Niacinamide
Tripeptide-29
Ceramide NP
Ceramide AP
Ceramide EOP
Sodium Hyaluronate
Phytosphingosine
Cholesterol
Panthenol
Sodium PCA
Adenosine
Lecithin
Arginine
Sodium Lauroyl Lactylate
Sodium Gluconate
Citric Acid
Isohexadecane
Xanthan Gum
Carbomer
Phenoxyethanol
Ethylhexylglycerin
Water, Ethyl Macadamiate, Glycerin, Cetearyl Alcohol, Propanediol, Triethylhexanoin, Sodium Acrylates Copolymer, Glyceryl Stearate, PEG-100 Stearate, Glycyrrhiza Glabra Root, Hydrolyzed Pumpkin Seedcake, Vaccinium Angustifolium Fruit Extract, Euterpe Oleracea Fruit Extract, Prunus Serotina Fruit Extract, Niacinamide, Tripeptide-29, Ceramide NP, Ceramide AP, Ceramide EOP, Sodium Hyaluronate, Phytosphingosine, Cholesterol, Panthenol, Sodium PCA, Adenosine, Lecithin, Arginine, Sodium Lauroyl Lactylate, Sodium Gluconate, Citric Acid, Isohexadecane, Xanthan Gum, Carbomer, Phenoxyethanol, Ethylhexylglycerin
Dimethicone
Isocetyl Stearate
Isopropyl Lauroyl Sarcosinate
Silica
Ammonium Polyacryloyldimethyl Taurate
Methyl Methacrylate Crosspolymer
Sodium Hydroxide
Poloxamer 338
Polysorbate 80
Mannose
Zinc PCA
2-Oleamido-1,3-Octadecanediol
Capryloyl Salicylic Acid
Caprylyl Glycol
Piroctone Olamine
Myristyl Myristate
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Sorbitan Oleate
Disodium EDTA
Potassium Cetyl Phosphate
Vitreoscilla Ferment
Aluminum Starch Octenylsuccinate
Glyceryl Stearate Se
Parfum
Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Silica, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, Sodium Hydroxide, Poloxamer 338, Polysorbate 80, Mannose, Xanthan Gum, Zinc PCA, Isohexadecane, 2-Oleamido-1,3-Octadecanediol, Capryloyl Salicylic Acid, Caprylyl Glycol, Piroctone Olamine, Myristyl Myristate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sorbitan Oleate, Disodium EDTA, Potassium Cetyl Phosphate, Vitreoscilla Ferment, Aluminum Starch Octenylsuccinate, Glyceryl Stearate Se, Parfum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.
Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.
Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.