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Skin science article

Paula's Choice Clear Pore Normalizing Cleanser Versus Paula's Choice Resist Perfectly Balanced Foaming Cleanser

Paula's Choice Clear Pore Normalizing Cleanser Versus Paula's Choice Resist Perfectly Balanced Foaming Cleanser This salicylic acid gel cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores. This mild cream cleanser is made to cleans

Paula's Choice Clear Pore Normalizing Cleanser Versus Paula's Choice Resist Perfectly Balanced Foaming Cleanser

This salicylic acid gel cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores.

This mild cream cleanser is made to cleanse without leaving your skin tight or dry.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Salicylic Acid

Water

Sodium Lauroyl Sarcosinate

Acrylates/Steareth-20 Methacrylate Copolymer

Glycerin

PEG-200 Hydrogenated Glyceryl Palmate

Sodium Laureth Sulfate

Arginine

Butylene Glycol

PEG-7 Glyceryl Cocoate

Panthenol

Disodium EDTA

Citric Acid

PEG-60 Hydrogenated Castor Oil

Sodium Citrate

Phenoxyethanol

Caprylyl Glycol

Chlorphenesin

Salicylic Acid, Water, Sodium Lauroyl Sarcosinate, Acrylates/Steareth-20 Methacrylate Copolymer, Glycerin, PEG-200 Hydrogenated Glyceryl Palmate, Sodium Laureth Sulfate, Arginine, Butylene Glycol, PEG-7 Glyceryl Cocoate, Panthenol, Disodium EDTA, Citric Acid, PEG-60 Hydrogenated Castor Oil, Sodium Citrate, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin

Sodium Lauroamphoacetate

Sodium Cocoyl Isethionate

Stearic Acid

Glycol Distearate

Helianthus Annuus Seed Oil

Acrylates Copolymer

Cetearyl Alcohol

Sodium Hyaluronate

Ceramide NP

Ceramide AP

Ceramide EOP

Phytosphingosine

Phospholipids

Sphingolipids

Lecithin

Cholesterol

Aloe Barbadensis Leaf Extract

Sodium Chloride

Sodium Hydroxide

Sodium Lauroyl Lactylate

Xanthan Gum

Carbomer

Hexylene Glycol

Water, Sodium Lauroamphoacetate, Sodium Cocoyl Isethionate, Stearic Acid, Glycerin, Glycol Distearate, Helianthus Annuus Seed Oil, Acrylates Copolymer, Cetearyl Alcohol, Sodium Hyaluronate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Phospholipids, Sphingolipids, Lecithin, Arginine, Cholesterol, Aloe Barbadensis Leaf Extract, Disodium EDTA, Sodium Chloride, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum, Carbomer, Hexylene Glycol, Phenoxyethanol, Caprylyl Glycol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  7. 07Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  8. 08However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  9. 09Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  10. 10In skincare formulas, citric acid can:
  11. 11While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  12. 12Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  13. 13Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  14. 14However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  15. 15Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  16. 16Topically, glycerin does several things at once:
  17. 17Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  18. 18Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  19. 19This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  20. 20Just know very high concentrations (>40%) can feel tacky in low humidity.
Source · skinsort.com
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Product index

Related product references

Product

Paula's Choice The Unscrub

Paula's Choice The Unscrub Paula's Choice The Unscrub ingredients explained: Aqua, Jojoba Esters (Cleansing Beads), Caprylic/Capric Triglyceride (Skin-Replenishing), Glycerin (Skin Replenis…

Source: incidecoder.comView reference →
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Comparison edit

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