Skin science article
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Dr. Lara Devgan Vitamin C+B+E Ferulic Serum
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Dr. Lara Devgan Vitamin C+B+E Ferulic Serum This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. This
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Dr. Lara Devgan Vitamin C+B+E Ferulic Serum
This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.
This brightening serum is formulated around Ascorbic Acid and Tocopherol to brighten dull-looking skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Pentaerythrityl Tetraisostearate
Isononyl Isononanoate
Butylene Glycol
Bakuchiol
Arachidyl Alcohol
Glyceryl Polymethacrylate
Dimethicone Crosspolymer
Behenyl Alcohol
Glycerin
PEG-75 Shea Butter Glycerides
Glyceryl Stearate
C12-15 Alkyl Benzoate
Polysorbate 20
Tetrahexyldecyl Ascorbate
Retinol
Ceramide Ng
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Dipotassium Glycyrrhizate
Glycyrrhiza Glabra Root Extract
Avena Sativa Kernel Extract
Arctium Lappa Root Extract
Salix Alba Bark Extract
Glycine Soja Sterols
Lecithin
Allantoin
Tocopheryl Acetate
Hydrolyzed Soy Protein
Palmitoyl Tripeptide-1
Sodium Hydroxide
Tribehenin
Caprylyl Glycol
Dipeptide-2
Polygonum Cuspidatum Root Extract
PEG-10 Phytosterol
PEG-8
Magnesium Aluminum Silicate
Arachidyl Glucoside
Chrysin
Pentylene Glycol
Sodium Acrylates Copolymer
Steareth-20
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Cetearyl Alcohol
Coco-Glucoside
Hesperidin Methyl Chalcone
N-Hydroxysuccinimide
Disodium EDTA
Phenoxyethanol
Benzoic Acid
Ethylhexylglycerin
Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin
Ascorbic Acid 15%
Tocopherol 1%
Ferulic Acid 0.5%
Acetyl Octapeptide-3
Ethoxydiglycol
PPG-26-Buteth-26
PEG-40 Hydrogenated Castor Oil
Panthenol
Triethanolamine
Sodium Metabisulfite
Ascorbic Acid 15%, Tocopherol 1%, Ferulic Acid 0.5%, Acetyl Octapeptide-3, Water, Ethoxydiglycol, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Glycerin, Panthenol, Sodium Hyaluronate, Phenoxyethanol, Triethanolamine, Sodium Metabisulfite
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!