Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice Defense Antioxidant Pore Purifier Versus Differin Adapalene Gel 0.1% Acne Treatment

Paula's Choice Defense Antioxidant Pore Purifier Versus Differin Adapalene Gel 0.1% Acne Treatment This pore-care treatment is formulated around Ascorbyl Glucoside and Salicylic Acid to refine the look of pores and balance excess oil. This acne treatment is fo

Paula's Choice Defense Antioxidant Pore Purifier Versus Differin Adapalene Gel 0.1% Acne Treatment

This pore-care treatment is formulated around Ascorbyl Glucoside and Salicylic Acid to refine the look of pores and balance excess oil.

This acne treatment is formulated around Adapalene to clear breakouts and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Butylene Glycol

Ethoxydiglycol

Glycerin

Ascorbyl Glucoside

Panthenol

Salicylic Acid

Camellia Sinensis Callus

Glycyrrhiza Glabra Root Extract

Potassium Azeloyl Diglycinate

Coffea Arabica Fruit Extract

Ceramide NP

Vitis Vinifera Seed Extract

Panax Ginseng Root Extract

Niacinamide

Phytic Acid

Epigallocatechin Gallate

Adenosine

Ubiquinone

Calendula Officinalis Flower Extract

Lonicera Caprifolium Flower Extract

Sodium Hyaluronate

Lecithin

Centella Asiatica Extract

Sucrose Stearate

Glycine Soja Seed Extract

Hydrogenated Lecithin

Carbomer

Tetrasodium Glutamate Diacetate

Caprylic/Capric Triglyceride

Caprylyl Glycol

Polysorbate 20

Polyglyceryl-10 Stearate

Hydroxyethylcellulose

Sodium Hydroxide

Ethylhexylglycerin

Phenoxyethanol

Water, Propanediol, Butylene Glycol, Ethoxydiglycol, Glycerin, Ascorbyl Glucoside, Panthenol, Salicylic Acid, Camellia Sinensis Callus, Glycyrrhiza Glabra Root Extract, Potassium Azeloyl Diglycinate, Coffea Arabica Fruit Extract, Ceramide NP, Vitis Vinifera Seed Extract, Panax Ginseng Root Extract, Niacinamide, Phytic Acid, Epigallocatechin Gallate, Adenosine, Ubiquinone, Calendula Officinalis Flower Extract, Lonicera Caprifolium Flower Extract, Sodium Hyaluronate, Lecithin, Centella Asiatica Extract, Sucrose Stearate, Glycine Soja Seed Extract, Hydrogenated Lecithin, Carbomer, Tetrasodium Glutamate Diacetate, Caprylic/Capric Triglyceride, Caprylyl Glycol, Polysorbate 20, Polyglyceryl-10 Stearate, Hydroxyethylcellulose, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol

Adapalene 0.1%

Disodium EDTA

Methylparaben

Poloxamer 182

Propylene Glycol

Adapalene 0.1%, Carbomer, Disodium EDTA, Methylparaben, Poloxamer 182, Propylene Glycol, Water, Sodium Hydroxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Dimethicone
  3. 03Glycerin
  4. 04Butylene Glycol
  5. 05Isononyl Isononanoate
  6. 06Castor Isostearate Succinate
  7. 07Glyceryl Stearate
  8. 08C12-15 Alkyl Benzoate
  9. 09Dimethicone Crosspolymer
  10. 10PEG-33
  11. 11Polysorbate 20
  12. 12Behenyl Alcohol
  13. 13PEG-100 Stearate
  14. 14Pentaerythrityl Tetraisostearate
  15. 15Polymethylsilsesquioxane
  16. 16Tetrahexyldecyl Ascorbate
  17. 17Retinol
  18. 18Ceramide Ng
  19. 19Palmitoyl Tetrapeptide-7
  20. 20Palmitoyl Hexapeptide-12
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side