Paula's Choice Extra Care Non-Greasy Sunscreen SPF 50 Versus La Roche-Posay Anthelios Ultra Comfort Cream SPF 50+

Paula's Choice Extra Care Non-Greasy Sunscreen SPF 50 Versus La Roche-Posay Anthelios Ultra Comfort Cream SPF 50+

This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Homosalate 10%

Benzophenone-3 6%

Ethylhexyl Salicylate 5%

Butyl Methoxydibenzoylmethane 3%

Octocrylene 2%

Water

Butylene Glycol

PEG-8

Polyethylene

Silica

Dimethicone

Picrasma Excelsa Wood Extract

Sodium Ascorbyl Phosphate

Retinyl Palmitate

Tocopherol

Tocopheryl Acetate

Titanium Dioxide

Aloe Barbadensis Leaf Juice

Bentonite

Methyl Glucose Sesquistearate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Polyacrylate

Kaolin

Ethylhexylglycerin

Disodium EDTA

Sodium Hydroxide

Phenoxyethanol

Chlorphenesin

Homosalate 10%, Benzophenone-3 6%, Ethylhexyl Salicylate 5%, Butyl Methoxydibenzoylmethane 3%, Octocrylene 2%, Water, Butylene Glycol, PEG-8, Polyethylene, Silica, Dimethicone, Picrasma Excelsa Wood Extract, Sodium Ascorbyl Phosphate, Retinyl Palmitate, Tocopherol, Tocopheryl Acetate, Titanium Dioxide, Aloe Barbadensis Leaf Juice, Bentonite, Methyl Glucose Sesquistearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Polyacrylate, Kaolin, Ethylhexylglycerin, Disodium EDTA, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin

Diisopropyl Sebacate

Glycerin

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Alcohol Denat.

Propanediol

Ethylhexyl Salicylate

Ethylhexyl Triazone

C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer

Drometrizole Trisiloxane

Butyl Methoxydibenzoylmethane

Aluminum Starch Octenylsuccinate

Isopropyl Lauroyl Sarcosinate

Ammonium Acrylates Copolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Caprylyl Glycol

Citric Acid

Scutellaria Baicalensis Extract

Scutellaria Baicalensis Root Extract

T-Butyl Alcohol

Terephthalylidene Dicamphor Sulfonic Acid

Triethanolamine

Xanthan Gum

Water, Diisopropyl Sebacate, Glycerin, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Alcohol Denat., Propanediol, Ethylhexyl Salicylate, Ethylhexyl Triazone, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Drometrizole Trisiloxane, Butyl Methoxydibenzoylmethane, Aluminum Starch Octenylsuccinate, Silica, Tocopherol, Isopropyl Lauroyl Sarcosinate, Ammonium Acrylates Copolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Glycol, Citric Acid, Disodium EDTA, Scutellaria Baicalensis Extract, Scutellaria Baicalensis Root Extract, T-Butyl Alcohol, Terephthalylidene Dicamphor Sulfonic Acid, Triethanolamine, Xanthan Gum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).

It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.

This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.

Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.

The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.

It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.

Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's.

It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm.

You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.

The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.

Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.

The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.

Usage levels vary around the world:

Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.

The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).

You might have seen scary headlines about sunscreen getting into your blood.

In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.

Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.

The researchers were clear that the results are no reason to stop wearing sunscreen.

Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.

Though it has exfoliant properties, the function of silica varies depending on the product.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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