Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice Hyaluronic Acid Booster Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum

Paula's Choice Hyaluronic Acid Booster Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum This hydrating treatment is formulated around Sodium Hyaluronate and Hyaluronic Acid to hydrate skin and strengthen the skin barrier. This hydrating serum is formu

Paula's Choice Hyaluronic Acid Booster Versus L'Oreal Revitalift 1.5% Pure Hyaluronic Acid Serum

This hydrating treatment is formulated around Sodium Hyaluronate and Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

This hydrating serum is formulated around Sodium Hyaluronate and Dipeptide Diaminobutyroyl Benzylamide Diacetate to hydrate skin and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Sodium Hyaluronate

Hyaluronic Acid

Ceramide NP

Ceramide AP

Ceramide EOP

Phytosphingosine

Yeast Extract

Adenosine

Cholesterol

Panthenol

Silanetriol

Butylene Glycol

Sodium Lauroyl Lactylate

Carbomer

Xanthan Gum

Citric Acid

Sodium Hydroxide

Polysorbate 20

Ethylhexylglycerin

Phenoxyethanol

Water, Glycerin, Sodium Hyaluronate, Hyaluronic Acid, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Yeast Extract, Adenosine, Cholesterol, Panthenol, Silanetriol, Butylene Glycol, Sodium Lauroyl Lactylate, Carbomer, Xanthan Gum, Citric Acid, Sodium Hydroxide, Polysorbate 20, Ethylhexylglycerin, Phenoxyethanol

Hydroxyethylpiperazine Ethane Sulfonic Acid

PEG-60

Hydrogenated Castor Oil

Secale Cereale Seed Extract

Calcium Pantothenate

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Ascorbyl Glucoside

Disodium EDTA

Pentylene Glycol

Chlorphenesin

Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, PEG-60, Hydrogenated Castor Oil, Secale Cereale Seed Extract, Calcium Pantothenate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Ascorbyl Glucoside, Disodium EDTA, Pentylene Glycol, Phenoxyethanol, Chlorphenesin

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  4. 04Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  5. 05In practice, that translates to a long shelf life and a consistently elegant skin feel.
  6. 06While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  7. 07Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  8. 08This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  9. 09This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  10. 10PEG-20 Glyceryl Triisostearate is a synthetic, oil-loving helper ingredient that does two jobs:
  11. 11This ingredient is made by joining three building blocks: PEG, Isostearic Acid and glycerin. The PEG gives it the oil-and-water blending power.
  12. 12This ingredient has been found safe for use in cosmetics and broader PEG family testing shows minimal irritation/sensitization. The molecule's large size also means it isn't expected to penetrate skin to any meaningful degree.
  13. 13Fungal acne note: This ingredient may not be fungal acne safe due to isostearic acid (C18). Isostearic acid falls into the C11-24 range that Malassezia can feed on.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side