Skin science article
Paula's Choice Omega+ Complex Moisturizer Versus Topicals Faded Brightening + Clearing Serum
Paula's Choice Omega+ Complex Moisturizer Versus Topicals Faded Brightening + Clearing Serum This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Linoleic Acid to strengthen the skin barrier and hydrate skin. This brightening se
Paula's Choice Omega+ Complex Moisturizer Versus Topicals Faded Brightening + Clearing Serum
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Linoleic Acid to strengthen the skin barrier and hydrate skin.
This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butyrospermum Parkii Butter
Ceteareth-6 Olivate
Butylene Glycol
C13-15 Alkane
Glycerin
Glyceryl Stearate
Polyglyceryl-4 Laurate
Decyl Oleate
Linum Usitatissimum Seed Oil
Salvia Hispanica Seed Oil
Olea Europaea Fruit Oil
Passiflora Edulis Seed Oil
Borago Officinalis Seed Oil
Hydrogenated Olive Oil
Psidium Guajava Fruit Extract
Olea Europaea Oil Unsaponifiables
Limnanthes Alba Seed Oil
Linoleic Acid
Linolenic Acid
Oleic Acid
Euterpe Oleracea Sterols
Ceramide AP
Ceramide EOP
Ceramide NP
Serine
Alanine
Glycine
Proline
Lysine Hcl
Threonine
Arginine
Squalane
Cholesterol
Phytosphingosine
Anastatica Hierochuntica Extract
Lecithin
Sodium Hyaluronate
Sodium Lactate
Boerhavia Diffusa Root Extract
Adenosine
Phytic Acid
Glutamic Acid
Betaine
Pullulan
PCA
Sodium PCA
Carbomer
Sodium Polyacrylate Starch
Sclerotium Gum
Xanthan Gum
Sodium Lauroyl Lactylate
Phenoxyethanol
Ethylhexylglycerin
Water, Butyrospermum Parkii Butter, Ceteareth-6 Olivate, Butylene Glycol, C13-15 Alkane, Glycerin, Glyceryl Stearate, Polyglyceryl-4 Laurate, Decyl Oleate, Linum Usitatissimum Seed Oil, Salvia Hispanica Seed Oil, Olea Europaea Fruit Oil, Passiflora Edulis Seed Oil, Borago Officinalis Seed Oil, Hydrogenated Olive Oil, Psidium Guajava Fruit Extract, Olea Europaea Oil Unsaponifiables, Limnanthes Alba Seed Oil, Linoleic Acid, Linolenic Acid, Oleic Acid, Euterpe Oleracea Sterols, Ceramide AP, Ceramide EOP, Ceramide NP, Serine, Alanine, Glycine, Proline, Lysine Hcl, Threonine, Arginine, Squalane, Cholesterol, Phytosphingosine, Anastatica Hierochuntica Extract, Lecithin, Sodium Hyaluronate, Sodium Lactate, Boerhavia Diffusa Root Extract, Adenosine, Phytic Acid, Glutamic Acid, Betaine, Pullulan, PCA, Sodium PCA, Carbomer, Sodium Polyacrylate Starch, Sclerotium Gum, Xanthan Gum, Sodium Lauroyl Lactylate, Phenoxyethanol, Ethylhexylglycerin
Caprylic/Capric Triglyceride
Niacinamide
Tranexamic Acid
Arbutin
Simmondsia Chinensis Seed Oil
Behenyl Alcohol
Glyceryl Behenate
Kojic Acid
Oxidized Glutathione
Ceteareth-20
Zinc Ricinoleate
Arginine Hcl
Azelaic Acid
Ceteareth-12
Cetearyl Alcohol
Cetyl Palmitate
Tetrahydroxypropyl Ethylenediamine
Curcuma Longa Root Extract
Sodium Lauroyl Sarcosinate
Trisodium Ethylenediamine Disuccinate
Allantoin
Dimethylmethoxy Chromanyl Palmitate
Centella Asiatica Leaf Extract
Melatonin
Glycyrrhiza Glabra Root Extract
Water, Caprylic/Capric Triglyceride, Glycerin, Niacinamide, Butyrospermum Parkii Butter, Tranexamic Acid, Glyceryl Stearate, Arbutin, Simmondsia Chinensis Seed Oil, Behenyl Alcohol, Glyceryl Behenate, Kojic Acid, Oxidized Glutathione, Phenoxyethanol, Ceteareth-20, Lecithin, Sclerotium Gum, Zinc Ricinoleate, Arginine Hcl, Azelaic Acid, Squalane, Ceteareth-12, Cetearyl Alcohol, Cetyl Palmitate, Tetrahydroxypropyl Ethylenediamine, Curcuma Longa Root Extract, Sodium Lauroyl Sarcosinate, Trisodium Ethylenediamine Disuccinate, Phytic Acid, Allantoin, Dimethylmethoxy Chromanyl Palmitate, Ethylhexylglycerin, Centella Asiatica Leaf Extract, Melatonin, Glycyrrhiza Glabra Root Extract
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Phytic Acid is a gentle AHA and antioxidant. AHAs are chemical exfoliants that help remove dead skin cells. Phytic Acid has a slight and mild exfoliating effect.
The chemical makeup makes it classified as an AHA, much like lactic acid.
In some cases, it is a chelating agent. Chelating agents help prevent metals from binding to water, helping to stabilize the ingredients in a product.
An interesting fact about phytic acid is that it is considered an antinutrient. People do not have the enzyme needed to properly breakdown and digest phytic acid. When ingested, phytic acid binds to minerals and prevents them from being absorbed.
Read more about some other popular AHA's here:
Sclerotium Gum is a natural sugar-based fiber made by fermenting a fungus called Sclerotium rolfsii. It's often used as the plant-friendly alternative for synthetic thickeners like carbomer.
In skincare, it works as a thickener, gel former, and stabilizer that keeps heavy ingredients suspended so a product does not separate.
It is non-ionic and forms a triple helix in solution. This is just a fancy way of saying it builds a smooth, cushiony, and non-sticky gel that feels silkier than many other gums.
Another perk of this ingredient is that it is very sturdy and holds up across a wide pH range (~2-11). It's also good at resisting heat and hydrolysis.
Since it holds water at the skin surface, it can provide some light hydration as well.
Typical use levels are around 0.25-2%; formulators usually use 0.2-0.5% to thicken lotions and up to 2% for a firmer gel base.
This ingredient has been found safe in cosmetics with no meaningful evidence of skin sensitization.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!