Skin science article
Paula's Choice Peptide Booster Versus Paula's Choice Perfect Cleansing Oil
Paula's Choice Peptide Booster Versus Paula's Choice Perfect Cleansing Oil This anti-aging treatment is formulated around Tripeptide-1 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This oil-based makeup remover is made to d
Paula's Choice Peptide Booster Versus Paula's Choice Perfect Cleansing Oil
This anti-aging treatment is formulated around Tripeptide-1 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.
This oil-based makeup remover is made to dissolve makeup, sunscreen, and daily buildup.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
PEG-8 Dimethicone
Tripeptide-1
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Myristoyl Hexapeptide-16
Myristoyl Pentapeptide-17
Hexanoyl Dipeptide-3 Norleucine Acetate
Azelaoyl Bis-Dipeptide-10
Glycoproteins
Phospholipids
Adenosine
Dipotassium Glycyrrhizate
Arginine
Valine
Glycine
Alanine
Glutamic Acid
Serine
Threonine
Yeast Extract
Isoleucine
Proline
Histidine
Phenylalanine
PCA
Phytic Acid
Panax Ginseng Root Extract
Sodium PCA
Psidium Guajava Fruit Extract
Euterpe Oleracea Fruit Extract
Ahnfeltiopsis Concinna Extract
Dextran
Hydrolyzed Silk
Lecithin
Glyceryl Polymethacrylate
C12-16 Pareth-9
Trideceth-12
Sodium Lactate
Carbomer
Aspartic Acid
Polysorbate 20
Butylene Glycol
Caprylyl Glycol
PEG-8
C11-15 Pareth-7
Guar Hydroxypropyltrimonium Chloride
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Ectoin
Citrate Buffer
Trimethylsiloxyamodimethicone
Phenoxyethanol
Sodium Hydroxide
Ethylhexylglycerin
Water, Glycerin, PEG-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Phospholipids, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, PCA, Phytic Acid, Panax Ginseng Root Extract, Sodium PCA, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, PEG-8, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin
Caprylic/Capric Triglyceride
Helianthus Annuus Seed Oil
Mipa-Laureth Sulfate
Laureth-4
Laureth-7
Triethylhexanoin
Cocos Nucifera Fruit Extract
Limnanthes Alba Seed Oil
Simmondsia Chinensis Seed Oil
Vitis Vinifera
Butyrospermum Parkii Butter Unsaponifiables
Tocopherol
Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Mipa-Laureth Sulfate, Laureth-4, Laureth-7, Triethylhexanoin, Cocos Nucifera Fruit Extract, Limnanthes Alba Seed Oil, Simmondsia Chinensis Seed Oil, Vitis Vinifera, Butyrospermum Parkii Butter Unsaponifiables, Tocopherol, Phenoxyethanol, Ethylhexylglycerin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.