Skin science article
Paula's Choice Phytoestrogen Elasticity Renewal Serum Versus Paula's Choice Peptide Booster
Paula's Choice Phytoestrogen Elasticity Renewal Serum Versus Paula's Choice Peptide Booster This anti-aging serum is formulated around Resveratrol to soften the look of wrinkles. This anti-aging treatment is formulated around Tripeptide-1 and Palmitoyl Tripept
Paula's Choice Phytoestrogen Elasticity Renewal Serum Versus Paula's Choice Peptide Booster
This anti-aging serum is formulated around Resveratrol to soften the look of wrinkles.
This anti-aging treatment is formulated around Tripeptide-1 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cyclodextrin
Glycerin
Coco-Caprylate
Squalane
Saccharide Isomerate
Propanediol
Sodium Acrylates Copolymer
Hydrogenated Polydecene
Glycine Soja Seed Extract
Equol
Resveratrol
Xanthan Gum
Cetyl Alcohol
Tocopherol
Daidzein
Genistein
Linum Usitatissimum Seed Oil
Helianthus Annuus Seed Oil
Phospholipids
Polyglyceryl-10 Stearate
Citric Acid
Ethylhexylglycerin
Glycine Soja Oil
Engelhardtia Chrysolepis Leaf Extract
Sodium Phytate
Sodium Citrate
Phenoxyethanol
Water, Cyclodextrin, Glycerin, Coco-Caprylate, Squalane, Saccharide Isomerate, Propanediol, Sodium Acrylates Copolymer, Hydrogenated Polydecene, Glycine Soja Seed Extract, Equol, Resveratrol, Xanthan Gum, Cetyl Alcohol, Tocopherol, Daidzein, Genistein, Linum Usitatissimum Seed Oil, Helianthus Annuus Seed Oil, Phospholipids, Polyglyceryl-10 Stearate, Citric Acid, Ethylhexylglycerin, Glycine Soja Oil, Engelhardtia Chrysolepis Leaf Extract, Sodium Phytate, Sodium Citrate, Phenoxyethanol
PEG-8 Dimethicone
Tripeptide-1
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Myristoyl Hexapeptide-16
Myristoyl Pentapeptide-17
Hexanoyl Dipeptide-3 Norleucine Acetate
Azelaoyl Bis-Dipeptide-10
Glycoproteins
Adenosine
Dipotassium Glycyrrhizate
Arginine
Valine
Glycine
Alanine
Glutamic Acid
Serine
Threonine
Yeast Extract
Isoleucine
Proline
Histidine
Phenylalanine
PCA
Phytic Acid
Panax Ginseng Root Extract
Sodium PCA
Psidium Guajava Fruit Extract
Euterpe Oleracea Fruit Extract
Ahnfeltiopsis Concinna Extract
Dextran
Hydrolyzed Silk
Lecithin
Glyceryl Polymethacrylate
C12-16 Pareth-9
Trideceth-12
Sodium Lactate
Carbomer
Aspartic Acid
Polysorbate 20
Butylene Glycol
Caprylyl Glycol
PEG-8
C11-15 Pareth-7
Guar Hydroxypropyltrimonium Chloride
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Ectoin
Citrate Buffer
Trimethylsiloxyamodimethicone
Sodium Hydroxide
Water, Glycerin, PEG-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Phospholipids, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, PCA, Phytic Acid, Panax Ginseng Root Extract, Sodium PCA, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, PEG-8, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.
In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).
Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.
They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.
Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.
Some types of phospholipids include:
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!