Paula's Choice RESIST Daily Smoothing Treatment With 5% AHA Versus CeraVe Skin Renewing Nightly Exfoliating Treatment

Paula's Choice RESIST Daily Smoothing Treatment With 5% AHA Versus CeraVe Skin Renewing Nightly Exfoliating Treatment

This smoothing exfoliator is formulated around Glycolic Acid and Palmitoyl Hexapeptide-12 to refine skin texture and soften the look of wrinkles.

This smoothing treatment is formulated around Glycolic Acid and Lactic Acid to refine skin texture and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycolic Acid

Cetyl Alcohol

Butylene Glycol

Polyacrylamide

Dimethicone

PPG-14 Butyl Ether

Palmitoyl Hexapeptide-12

Ceramide Ng

Tetrahydrodiferuloylmethane

Tetrahydrodemethoxydiferuloylmethane

Tetrahydrobisdemethoxydiferuloylmethane

Epigallocatechin Gallate

Salicylic Acid

Disodium Lauriminodipropionate Tocopheryl Phosphates

PEG-10 Phytosterol

Vanilla Planifolia Fruit Extract

Bisabolol

Allantoin

Cyclopentasiloxane

Cyclohexasiloxane

Dimethiconol

Tribehenin

C12-15 Alkyl Benzoate

PEG-40 Stearate

Sorbitan Stearate

Pvm/Ma Decadiene Crosspolymer

Disodium EDTA

C13-14 Isoparaffin

Laureth-7

Sodium Hydroxide

Caprylyl Glycol

Caprylic/Capric Triglyceride

Hexylene Glycol

Ethylhexylglycerin

Phenoxyethanol

Water, Glycolic Acid, Cetyl Alcohol, Butylene Glycol, Polyacrylamide, Dimethicone, PPG-14 Butyl Ether, Palmitoyl Hexapeptide-12, Ceramide Ng, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Epigallocatechin Gallate, Salicylic Acid, Disodium Lauriminodipropionate Tocopheryl Phosphates, PEG-10 Phytosterol, Vanilla Planifolia Fruit Extract, Bisabolol, Allantoin, Cyclopentasiloxane, Cyclohexasiloxane, Dimethiconol, Tribehenin, C12-15 Alkyl Benzoate, PEG-40 Stearate, Sorbitan Stearate, Pvm/Ma Decadiene Crosspolymer, Disodium EDTA, C13-14 Isoparaffin, Laureth-7, Sodium Hydroxide, Caprylyl Glycol, Caprylic/Capric Triglyceride, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol

Glycerin

Cetearyl Ethylhexanoate

Cetearyl Alcohol

Lactic Acid

Dipotassium Glycyrrhizate

Polyacrylate Crosspolymer-6

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Cetearyl Glucoside

Behentrimonium Methosulfate

Triethyl Citrate

Sodium Hyaluronate

Sodium Lauroyl Lactylate

Cholesterol

Phenylethyl Resorcinol

Isopropyl Myristate

Citric Acid

Trisodium Ethylenediamine Disuccinate

Xanthan Gum

Phytosphingosine

Benzoic Acid

Water, Glycerin, Cetearyl Ethylhexanoate, Cetearyl Alcohol, Dimethicone, Glycolic Acid, Lactic Acid, Sodium Hydroxide, Dipotassium Glycyrrhizate, Polyacrylate Crosspolymer-6, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Cetearyl Glucoside, Behentrimonium Methosulfate, Triethyl Citrate, Sodium Hyaluronate, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Phenylethyl Resorcinol, Isopropyl Myristate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Phytosphingosine, Benzoic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.

It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.

Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.

AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.

Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.

Overall, glycolic acid helps with:

Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.

To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).

The pH and concentration of a product are key to its effectiveness:

It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.

Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.

If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.

Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.

Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.

Read more about some other popular AHA's here:

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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