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Skin science article

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Go-To Skincare Much Brighter Skin

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Go-To Skincare Much Brighter Skin This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm redness. This brightening serum is for

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Go-To Skincare Much Brighter Skin

This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm redness.

This brightening serum is formulated around Sodium Ascorbyl Phosphate and Niacinamide to brighten dull-looking skin and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cyclopentasiloxane

Butylene Glycol

Dimethicone

Glycerin

Polysorbate 20

Polysilicone-11

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Hyaluronic Acid

Resveratrol

Niacinamide

Quercetin

Adenosine

Tetrahexyldecyl Ascorbate

Tocopherol

Phospholipids

Ubiquinone

Epigallocatechin Gallate

Sea Whip Extract

Bisabolol

Beta-Glucan

Phytic Acid

Xanthan Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

Water, Cyclopentasiloxane, Butylene Glycol, Dimethicone, Glycerin, Polysorbate 20, Polysilicone-11, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Hyaluronic Acid, Resveratrol, Niacinamide, Quercetin, Adenosine, Tetrahexyldecyl Ascorbate, Tocopherol, Phospholipids, Ubiquinone, Epigallocatechin Gallate, Sea Whip Extract, Bisabolol, Beta-Glucan, Phytic Acid, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol

Sodium Ascorbyl Phosphate

Coco-Caprylate

Cetearyl Olivate

Citric Acid

Sorbitan Olivate

Glyceryl Caprylate

Saccharide Isomerate

Jojoba Esters

Zingiber Officinale Root Extract

Helianthus Annuus Seed Oil

Terminalia Ferdinandiana Fruit Extract

Sodium Hyaluronate

Rosmarinus Officinalis Leaf Extract

Polyglycerin-3

Sodium Citrate

Caprylhydroxamic Acid

Lecithin

Sclerotium Gum

Sodium Phytate

Alcohol Denat.

Silica

Pullulan

Helianthus Annuus Seed Wax

Parfum

Water, Sodium Ascorbyl Phosphate, Coco-Caprylate, Glycerin, Niacinamide, Cetearyl Olivate, Citric Acid, Sorbitan Olivate, Glyceryl Caprylate, Xanthan Gum, Saccharide Isomerate, Jojoba Esters, Tocopherol, Bisabolol, Zingiber Officinale Root Extract, Helianthus Annuus Seed Oil, Terminalia Ferdinandiana Fruit Extract, Sodium Hyaluronate, Rosmarinus Officinalis Leaf Extract, Polyglycerin-3, Sodium Citrate, Caprylhydroxamic Acid, Lecithin, Sclerotium Gum, Sodium Phytate, Alcohol Denat., Silica, Pullulan, Helianthus Annuus Seed Wax, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
  4. 04As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
  5. 05It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
  6. 06A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
  7. 07Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
  8. 08It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
  9. 09This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
  10. 10Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
  11. 11The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
  12. 12It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
  13. 13Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
  14. 14Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  15. 15Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  16. 16Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  17. 17Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  18. 18What it does:
  19. 19Dimethicone comes in different viscosities:
  20. 20Depending on the viscosity, dimethicone has different properties.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

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