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Paula's Choice Resist Weightless Advanced Repairing Toner Versus Niod Superoxide Dismutase Saccharide Mist

Paula's Choice Resist Weightless Advanced Repairing Toner Versus Niod Superoxide Dismutase Saccharide Mist This anti-aging toner is formulated around Niacinamide and Acetyl Glucosamine to soften the look of wrinkles and strengthen the skin barrier. This calmin

Paula's Choice Resist Weightless Advanced Repairing Toner Versus Niod Superoxide Dismutase Saccharide Mist

This anti-aging toner is formulated around Niacinamide and Acetyl Glucosamine to soften the look of wrinkles and strengthen the skin barrier.

This calming toner is formulated around Superoxide Dismutase to calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Ethoxydiglycol

Niacinamide

Acetyl Glucosamine

Salix Nigra Bark Extract

Resveratrol

Sodium Hyaluronate

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Phospholipids

Epigallocatechin Gallate

Carnosine

Genistein

Glycyrrhiza Glabra Root Extract

Adenosine

Xanthan Gum

Citric Acid

Polysorbate 20

Butylene Glycol

Ethylhexylglycerin

Carbomer

Tetrasodium EDTA

Phenoxyethanol

Water, Glycerin, Ethoxydiglycol, Niacinamide, Acetyl Glucosamine, Salix Nigra Bark Extract, Resveratrol, Sodium Hyaluronate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Phospholipids, Epigallocatechin Gallate, Carnosine, Genistein, Glycyrrhiza Glabra Root Extract, Adenosine, Xanthan Gum, Citric Acid, Polysorbate 20, Butylene Glycol, Ethylhexylglycerin, Carbomer, Tetrasodium EDTA, Phenoxyethanol

Superoxide Dismutase

Malachite Extract

Pseudoalteromonas Exopolysaccharides

Mirabilis Jalapa Extract

Polypodium Vulgare Rhizome Extract

Cetraria Islandica Thallus Extract

Sphagnum Magellanicum Extract

Arginine

Propanediol

Pentylene Glycol

Sodium Salicylate

Gellan Gum

Sodium Chloride

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Tromethamine

Chlorphenesin

Water, Superoxide Dismutase, Malachite Extract, Pseudoalteromonas Exopolysaccharides, Mirabilis Jalapa Extract, Polypodium Vulgare Rhizome Extract, Cetraria Islandica Thallus Extract, Sphagnum Magellanicum Extract, Arginine, Propanediol, Glycerin, Pentylene Glycol, Butylene Glycol, Sodium Salicylate, Gellan Gum, Sodium Chloride, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Citric Acid, Tromethamine, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Paula's Choice 25% Vitamin C + Glutathione Clinical SerumIngredients explained

  1. 01Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
  2. 02It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
  3. 03Expand to read more
  4. 04Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
  5. 05One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
  6. 06Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in ex…
  7. 07So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it THDA …
  8. 08It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) a…
  9. 09With this context in mind let's see what THDA might be able to do. First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist.
  10. 10Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the…
  11. 11Third, THDA seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by …
  12. 12So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA…
  13. 13Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).
  14. 14Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
  15. 15As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's…
  16. 16As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build…
  17. 17A natural moisturizer that’s also in our skin
  18. 18A super common, safe, effective and cheap molecule used for more than 50 years
  19. 19Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  20. 20Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
Source · incidecoder.com
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Product index

Related product references

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Comparison edit

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