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Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50 Versus Azarine Hydrasoothe Sunscreen Gel SPF45 PA++++

Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50 Versus Azarine Hydrasoothe Sunscreen Gel SPF45 PA++++ This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. This chemical sunscreen covers most of the UV range, light

Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50 Versus Azarine Hydrasoothe Sunscreen Gel SPF45 PA++++

This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

This chemical sunscreen covers most of the UV range, lighter on the deep UVA that drives aging.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Butyl Methoxydibenzoylmethane 2%

Ethylhexyl Methoxycinnamate 7.5%

Ethylhexyl Salicylate 5%

Octocrylene 2%

Water

Glycerin

Silica

Dimethicone

Tocopherol

Chamomilla Recutita Flower Extract

Vitis Vinifera Seed Extract

Camellia Sinensis Leaf Extract

Camellia Oleifera Leaf Extract

Peucedanum Graveolens Extract

Sambucus Nigra Fruit Extract

Avena Sativa Bran Extract

Punica Granatum Extract

Lycium Barbarum Fruit Extract

Hydrogenated Lecithin

Titanium Dioxide

Dimethicone/Vinyl Dimethicone Crosspolymer

Diethylhexyl Syringylidenemalonate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Xanthan Gum

Sodium Carbomer

Benzyl Alcohol

Sodium Benzoate

Potassium Sorbate

Phenoxyethanol

Butyl Methoxydibenzoylmethane 2%, Ethylhexyl Methoxycinnamate 7.5%, Ethylhexyl Salicylate 5%, Octocrylene 2%, Water, Glycerin, Silica, Dimethicone, Tocopherol, Chamomilla Recutita Flower Extract, Vitis Vinifera Seed Extract, Camellia Sinensis Leaf Extract, Camellia Oleifera Leaf Extract, Peucedanum Graveolens Extract, Sambucus Nigra Fruit Extract, Avena Sativa Bran Extract, Punica Granatum Extract, Lycium Barbarum Fruit Extract, Hydrogenated Lecithin, Titanium Dioxide, Dimethicone/Vinyl Dimethicone Crosspolymer, Diethylhexyl Syringylidenemalonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Sodium Carbomer, Benzyl Alcohol, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol

Propanediol

Ethylhexyl Methoxycinnamate

Butyl Methoxydibenzoylmethane

Cucumis Sativus Fruit Extract

Octocrylene

Butylene Glycol

Aloe Barbadensis Leaf Juice

Polymethyl Methacrylate

Portulaca Oleracea Extract

Sodium Hyaluronate

Ectoin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Royal Jelly

Centella Asiatica Extract

Allantoin

Panthenol

Resveratrol

Lecithin

Disodium EDTA

Water, Glycerin, Propanediol, Ethylhexyl Methoxycinnamate, Butyl Methoxydibenzoylmethane, Cucumis Sativus Fruit Extract, Octocrylene, Butylene Glycol, Aloe Barbadensis Leaf Juice, Polymethyl Methacrylate, Portulaca Oleracea Extract, Sodium Hyaluronate, Camellia Sinensis Leaf Extract, Ectoin, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Royal Jelly, Centella Asiatica Extract, Allantoin, Panthenol, Resveratrol, Lecithin, Disodium EDTA

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).

It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.

This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.

Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.

The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.

It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.

Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.

Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.

Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.

Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.

In lab-grown skin models, this translated to younger, healthier, and stronger skin.

There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.

Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.

A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.

The quality of the extract matters a lot here:

Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.

Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).

This ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.

It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.

In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.

Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.

The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.

It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.

The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.

The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.

One last thing worth knowing for context:

Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.

Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.

This ingredient is also banned in Hawaii over coral reef concerns.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Octocrylene is an oil-soluble organic UV filter that mainly absorbs UVB and short wave UVA II light.

Its real superpower is teamwork: octocrylene is remarkably photostable and is most famous for stabilizing avobenzone (the workhorse UVA filter).

This ingredient is commonly used to enhance both UVB and UVA protection due to its unique property in stabilizing avobenzone. It also pulls double duty by boosting water resistance and giving formulas a smooth, spreadable feel.

The EU's Scientific Committee on Consumer Safety (SCCS) has deemed octocrylene to be safe as a UV-filter at concentrations up to 10% (capped at 9% in propellant sprays). The US also permits it up to 10%.

Two things worth knowing:

You'll usually see this ingredient used in concentrations between 2-10% (higher amounts when used as a stabilizer for avobenzone).

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  4. 04The way it works is fairly well mapped out:
  5. 05Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  6. 06The clinical backing is pretty solid too.
  7. 07A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  8. 08A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  9. 09On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  10. 10This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  11. 11Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  12. 12Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
  13. 13Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
  14. 14It plays several roles in a formula:
  15. 15Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
  16. 16Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
  17. 17However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
  18. 18Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
  19. 19Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
  20. 20Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
Source · skinsort.com
02

Product index

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Comparison edit

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