Skin science article
Paula's Choice Retinol Skin-Smoothing Body Treatment Versus SkinCeuticals Daily Moisture
Paula's Choice Retinol Skin-Smoothing Body Treatment Versus SkinCeuticals Daily Moisture This smoothing moisturizer is formulated around Retinol and Tetrahexyldecyl Ascorbate to refine skin texture and soften the look of wrinkles. This barrier-repair moisturiz
Paula's Choice Retinol Skin-Smoothing Body Treatment Versus SkinCeuticals Daily Moisture
This smoothing moisturizer is formulated around Retinol and Tetrahexyldecyl Ascorbate to refine skin texture and soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Tocopherol and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cetearyl Alcohol
Cetearyl Ethylhexanoate
Cyclopentasiloxane
Dimethicone
Glycerin
Butylene Glycol
Cetyl Palmitate
Butyrospermum Parkii Butter
Glyceryl Stearate
PEG-100 Stearate
Oenothera Biennis Oil
Vitis Vinifera Seed Oil
Cetyl Alcohol
Retinol
Tetrahexyldecyl Ascorbate
Tocopheryl Acetate
Caprylic/Capric Triglyceride
Panthenol
Carnosine
Dimethiconol
Dimethicone/Vinyl Dimethicone Crosspolymer
Beeswax
Magnesium Aluminum Silicate
Sodium Hydroxide
Xanthan Gum
Dicaprylyl Carbonate
Decylene Glycol
Disodium EDTA
Chlorphenesin
Phenoxyethanol
Water, Cetearyl Alcohol, Cetearyl Ethylhexanoate, Cyclopentasiloxane, Dimethicone, Glycerin, Butylene Glycol, Cetyl Palmitate, Butyrospermum Parkii Butter, Glyceryl Stearate, PEG-100 Stearate, Oenothera Biennis Oil, Vitis Vinifera Seed Oil, Cetyl Alcohol, Retinol, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Caprylic/Capric Triglyceride, Panthenol, Carnosine, Dimethiconol, Dimethicone/Vinyl Dimethicone Crosspolymer, Beeswax, Magnesium Aluminum Silicate, Sodium Hydroxide, Xanthan Gum, Dicaprylyl Carbonate, Decylene Glycol, Disodium EDTA, Chlorphenesin, Phenoxyethanol
Stearic Acid
Palmitic Acid
Tocopherol
Polymethylsilsesquioxane
Sorbitol
CI 77163
Sodium Hyaluronate
Hamamelis Virginiana Water
PEG-75 Stearate
Carbomer
Ethylhexyl Hydroxystearate
Allantoin
Ceteth-20
Triethanolamine
Caprylyl Glycol
Propylene Glycol
Steareth-20
Myristic Acid
Betaine
Chlorella Vulgaris Extract
Laminaria Saccharina Extract
Glucose
Chamomilla Recutita Flower Extract
Chamomilla Recutita Extract
Zingiber Officinale Root Extract
Sanguisorba Officinalis Root Extract
Cinnamomum Cassia Bark Extract
Thymus Vulgaris Flower/Leaf Extract
Retinyl Palmitate
Helianthus Annuus Seed Oil
Sodium Benzoate
Zinc Sulfate
Laminaria Ochroleuca Extract
Glycyrrhiza Glabra Root Extract
Urtica Dioica Extract
Equisetum Arvense Extract
Betula Alba Leaf Extract
Citric Acid
Potassium Sorbate
Cinnamal
Pyridoxine Hcl
Water, Glycerin, Cetyl Palmitate, Stearic Acid, Butylene Glycol, Palmitic Acid, Tocopherol, Dimethicone, Polymethylsilsesquioxane, Glyceryl Stearate, Sorbitol, CI 77163, Phenoxyethanol, PEG-100 Stearate, Sodium Hyaluronate, Hamamelis Virginiana Water, PEG-75 Stearate, Cetyl Alcohol, Carbomer, Ethylhexyl Hydroxystearate, Allantoin, Panthenol, Ceteth-20, Triethanolamine, Caprylyl Glycol, Xanthan Gum, Propylene Glycol, Steareth-20, Disodium EDTA, Myristic Acid, Betaine, Chlorella Vulgaris Extract, Laminaria Saccharina Extract, Glucose, Chamomilla Recutita Flower Extract, Chamomilla Recutita Extract, Zingiber Officinale Root Extract, Sanguisorba Officinalis Root Extract, Cinnamomum Cassia Bark Extract, Thymus Vulgaris Flower/Leaf Extract, Retinyl Palmitate, Helianthus Annuus Seed Oil, Sodium Benzoate, Zinc Sulfate, Laminaria Ochroleuca Extract, Glycyrrhiza Glabra Root Extract, Urtica Dioica Extract, Equisetum Arvense Extract, Betula Alba Leaf Extract, Citric Acid, Potassium Sorbate, Cinnamal, Pyridoxine Hcl
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Cetyl Palmitate is a wax-ester that pulls triple duty as an emollient, thickener, and emulsion enhancer.
It helps enhance the texture of products by giving a smooth, silky feel while helping to stabilize the formula. The emollient action softens skin and reduces moisture loss.
This ingredient is considered safe and human testing of concentrations between 2.5-2.7% were found minimal irritation. Just know, there have been very rare cases of the palmitate family causing contact dermatitis.
This ingredient may not be fungal acne safe because it contains a C16 ester (palmitic acid) that falls into the C11-24 range that Malassezia can feed on.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.