Skin science article
Paula's Choice Skin Balancing Invisible Finish Moisture Gel Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer
Paula's Choice Skin Balancing Invisible Finish Moisture Gel Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer This pore-care moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to refine the look of pores and calm re
Paula's Choice Skin Balancing Invisible Finish Moisture Gel Versus Paula's Choice Clinical Ceramide-Enriched Firming Moisturizer
This pore-care moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to refine the look of pores and calm redness.
This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Retinol to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cyclopentasiloxane
Butylene Glycol
Glycerin
Bis-Phenylpropyl Dimethicone
Niacinamide
Laminaria Saccharina Extract
Avena Sativa Kernel Extract
Camellia Oleifera Leaf Extract
Vitis Vinifera Seed Extract
Triticum Vulgare Germ Oil
Tocopheryl Acetate
Phenyl Trimethicone
Dimethicone
Dipotassium Glycyrrhizate
Tetrahexyldecyl Ascorbate
Sodium Hyaluronate
Phospholipids
Superoxide Dismutase
Isohexadecane
Panthenol
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Sodium Carbomer
Dimethicone/Vinyl Dimethicone Crosspolymer
Polysorbate 80
Hydroxyethylcellulose
Ethylhexylglycerin
Phenoxyethanol
Water, Cyclopentasiloxane, Butylene Glycol, Glycerin, Bis-Phenylpropyl Dimethicone, Niacinamide, Laminaria Saccharina Extract, Avena Sativa Kernel Extract, Camellia Oleifera Leaf Extract, Vitis Vinifera Seed Extract, Triticum Vulgare Germ Oil, Tocopheryl Acetate, Phenyl Trimethicone, Dimethicone, Dipotassium Glycyrrhizate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Phospholipids, Superoxide Dismutase, Isohexadecane, Panthenol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Carbomer, Dimethicone/Vinyl Dimethicone Crosspolymer, Polysorbate 80, Hydroxyethylcellulose, Ethylhexylglycerin, Phenoxyethanol
Sodium Ascorbyl Phosphate
Cetyl Alcohol
Neopentyl Glycol Diheptanoate
Potassium Cetyl Phosphate
Glyceryl Stearate
PEG-100 Stearate
PEG-12 Glyceryl Dimyristate
Bis-Diglyceryl Polyacyladipate-2
Glyceryl Ascorbate
Retinol
Ceramide NP
Ceramide Ns
Ceramide AP
Ceramide EOP
Ceramide Eos
Cholesterol
Caprooyl Phytosphingosine
Caprooyl Sphingosine
Squalane
Punica Granatum Extract
Pongamia Glabra Seed Oil
Glycyrrhiza Glabra Root
Vitis Vinifera
Carnosine
Sodium PCA
Sodium Citrate
Ceteareth-25
Polysorbate 20
Ethylhexyl Stearate
Sodium Hydroxide
Trideceth-6
Propyl Gallate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Sodium Polyacrylate
Behenic Acid
Disodium EDTA
Caprylyl Glycol
Chlorphenesin
Water, Sodium Ascorbyl Phosphate, Cetyl Alcohol, Neopentyl Glycol Diheptanoate, Potassium Cetyl Phosphate, Glyceryl Stearate, PEG-100 Stearate, Glycerin, PEG-12 Glyceryl Dimyristate, Bis-Diglyceryl Polyacyladipate-2, Dimethicone, Glyceryl Ascorbate, Tetrahexyldecyl Ascorbate, Retinol, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide EOP, Ceramide Eos, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Squalane, Punica Granatum Extract, Pongamia Glabra Seed Oil, Glycyrrhiza Glabra Root, Vitis Vinifera, Tocopheryl Acetate, Carnosine, Panthenol, Sodium PCA, Butylene Glycol, Sodium Citrate, Ceteareth-25, Polysorbate 20, Ethylhexyl Stearate, Sodium Hydroxide, Trideceth-6, Propyl Gallate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Behenic Acid, Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!