Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

PCA Skin Pro-Max Age Renewal Advanced Serum Versus Plated Skin Science Intense Serum

PCA Skin Pro-Max Age Renewal Advanced Serum Versus Plated Skin Science Intense Serum This anti-aging serum is formulated around Sodium Hyaluronate and Acetyl Octapeptide-3 to soften the look of wrinkles and hydrate skin. This anti-aging serum is formulated aro

PCA Skin Pro-Max Age Renewal Advanced Serum Versus Plated Skin Science Intense Serum

This anti-aging serum is formulated around Sodium Hyaluronate and Acetyl Octapeptide-3 to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Panthenol and Hyaluronic Acid to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Polysilicone-11

Propanediol

Glycerin

Butylene Glycol

PPG-3 Benzyl Ether Myristate

Polysorbate 20

Sodium Polyacryloyldimethyl Taurate

Caprylyl Glycol

Sodium Benzoate

Hydroxypropyl Methylcellulose

Sodium Hyaluronate

Ethylene Brassylate

Pullulan

Hydrolyzed Hyaluronic Acid

Potassium Sorbate

Sodium Acetylated Hyaluronate

Lactic Acid

Laureth-12

Carnosine

Tricholoma Matsutake Extract

Phenoxyethanol

Hdi/Trimethylol Hexyllactone Crosspolymer

Polymethylsilsesquioxane

Anigozanthos Flavidus Extract

Porphyridium Cruentum Extract

Pentylene Glycol

Ethylhexylglycerin

Bacillus Ferment

Sodium Hyaluronate Crosspolymer

Acetyl Octapeptide-3

Acetyl Tripeptide-54 Amide

Acetyl Tripeptide-74 Amide

Palmitoyl Sh-Tripeptide-1 Amide

Palmitoyl Sh-Tripeptide-3 Amide

Ergothioneine

Water, Polysilicone-11, Propanediol, Glycerin, Butylene Glycol, PPG-3 Benzyl Ether Myristate, Polysorbate 20, Sodium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Sodium Benzoate, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Ethylene Brassylate, Pullulan, Hydrolyzed Hyaluronic Acid, Potassium Sorbate, Sodium Acetylated Hyaluronate, Lactic Acid, Laureth-12, Carnosine, Tricholoma Matsutake Extract, Phenoxyethanol, Hdi/Trimethylol Hexyllactone Crosspolymer, Polymethylsilsesquioxane, Anigozanthos Flavidus Extract, Porphyridium Cruentum Extract, Pentylene Glycol, Ethylhexylglycerin, Bacillus Ferment, Sodium Hyaluronate Crosspolymer, Acetyl Octapeptide-3, Acetyl Tripeptide-54 Amide, Acetyl Tripeptide-74 Amide, Palmitoyl Sh-Tripeptide-1 Amide, Palmitoyl Sh-Tripeptide-3 Amide, Ergothioneine

Panthenol

Human Platelet Extract

Polyacrylate Crosspolymer-6

Hyaluronic Acid

1,2-Hexanediol

Hydrolyzed Gelatin

Arginine

Silanetriol

Water, Glycerin, Pentylene Glycol, Panthenol, Human Platelet Extract, Polyacrylate Crosspolymer-6, Hyaluronic Acid, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Arginine, Silanetriol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  4. 04Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  5. 05Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  6. 06Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  7. 07What it does:
  8. 08Dimethicone comes in different viscosities:
  9. 09Depending on the viscosity, dimethicone has different properties.
  10. 10Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  11. 11This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  12. 12Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  13. 13Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  14. 14The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  15. 15Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  16. 16Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  17. 17Topically, glycerin does several things at once:
  18. 18Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  19. 19Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  20. 20This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Source · skinsort.com
02

Product index

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03

Comparison edit

Read side by side