Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

PCA Skin ReBalance Versus Cetaphil Moisturising Lotion

PCA Skin ReBalance Versus Cetaphil Moisturising Lotion This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier. This barrier-repair moisturizer is formulated around Panthenol and Niacinamide to st

PCA Skin ReBalance Versus Cetaphil Moisturising Lotion

This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier.

This barrier-repair moisturizer is formulated around Panthenol and Niacinamide to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Ethylhexyl Isononanoate

Glycereth-26

Butylene Glycol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Phenoxyethanol

Niacinamide

Carbomer

Polyisobutene

Caprylyl Glycol

Bisabolol

Sodium Hydroxide

Ethylhexylglycerin

Hexylene Glycol

PEG-7 Trimethylolpropane Coconut Ether

Tocopheryl Acetate

Oenothera Biennis Oil

Borago Officinalis Seed Oil

Aloe Barbadensis Leaf Juice

Sodium Hyaluronate

Water, Ethylhexyl Isononanoate, Glycereth-26, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Niacinamide, Carbomer, Polyisobutene, Caprylyl Glycol, Bisabolol, Sodium Hydroxide, Ethylhexylglycerin, Hexylene Glycol, PEG-7 Trimethylolpropane Coconut Ether, Tocopheryl Acetate, Oenothera Biennis Oil, Borago Officinalis Seed Oil, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate

Glycerin

Isopropyl Palmitate

Cetearyl Alcohol

Ceteareth-20

Panthenol

Dimethicone

Persea Gratissima Oil

Helianthus Annuus Seed Oil

Pantolactone

Glyceryl Stearate

Sodium Benzoate

Benzyl Alcohol

Citric Acid

Water, Glycerin, Isopropyl Palmitate, Cetearyl Alcohol, Ceteareth-20, Panthenol, Niacinamide, Tocopheryl Acetate, Dimethicone, Persea Gratissima Oil, Helianthus Annuus Seed Oil, Pantolactone, Glyceryl Stearate, Sodium Benzoate, Benzyl Alcohol, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

PCA Skin Sheer Tint Broad Spectrum SPF 45Ingredients explained

  1. 01Titanium Dioxide is one of the two members of the elite sunscreen group called physical sunscreens (or inorganic sunscreens if you’re a science geek and want to be precise).
  2. 02Traditionally, UV-filters are categorized as either chemical or physical. The big difference is supposed to be that chemical agents absorb UV-light while physical agents reflect it like a bunch of mini umbrellas on top of the skin. While this catego…
  3. 03Expand to read more
  4. 04Anyway, it doesn't matter if it reflects or absorbs, Titanium Dioxide is a pretty awesome sunscreen agent for two main reasons: it gives a nice broad spectrum coverage and it's highly stable. Its protection is very good between 290 - 350 nm (UVB and…
  5. 05The disadvantage of Titanium Dioxide is that it's not cosmetically elegant, meaning it's a white, "unspreadable" mess. Sunscreens containing Titanium Dioxide are often hard to spread on the skin and they leave a disturbing whitish tint. The cosmetic…
  6. 06The main concern with nanoparticles is that they are so tiny that they are absorbed into the skin more than we want them (ideally sunscreen should remain on the surface of the skin). Once absorbed they might form unwanted complexes with proteins and…
  7. 07All in all, Titanium Dioxide is a famous sunscreen agent and for good reason, it gives broad spectrum UV protection (best at UVB and UVA II), it's highly stable, and it has a good safety profile. It's definitely one of the best UV-filter agents we h…
  8. 08When it comes to sunscreen agents, Zinc Oxide is pretty much in a league of its own. It's a physical (or inorganic) sunscreen that has a lot in common with fellow inorganic sunscreen Titanium Dioxide (TiO2) but a couple of things make it superior ev…
  9. 09If physical sunscreens don't tell you anything, go ahead and read about the basics here. Most of what we wrote about Titanium Dioxide is also true for Zinc Oxide so we will focus here on the differences.
  10. 10The first main difference is that while TiO2 gives a nice broad spectrum protection, Zinc Oxide has an even nicer and even broader spectrum protection. It protects against UVB, UVA II, and UVA I almost uniformly, and is considered to be the broadest…
  11. 11It's also highly stable and non-irritating. So much so that Zinc Oxide also counts as a skin protectant and anti-irritant. It's also often used to treat skin irritations such as diaper rash.
  12. 12As for the disadvantages, Zinc Oxide is also not cosmetically elegant. It leaves a disturbing whitish tint on the skin, although, according to a 2000 research paper by Dr. Pinnell, it's slightly less white than TiO2. Still, it's white and disturbing…
  13. 13We wrote more about nanoparticles and the concerns around them here, but the gist is that if nanoparticles were absorbed into the skin that would be a reason for legitimate health concerns. But luckily, so far research shows that sunscreen nanoparti…
  14. 14All in all, if you've found a Zinc Oxide sunscreen that you are happy to use every single day, that's fantastic and we suggest you stick with it. It's definitely one of the best, or probably even the best option out there for sun protection availabl…
  15. 15A multi-functional helper ingredient that's used mainly as a pigment carrier. The pigment can be an inorganic sunscreen (such as titanium dioxide) or a colorant that is blended with alumina platelets and then often coated with some kind of silicone …
  16. 16Other than that, alumina can also be used as an absorbent (sometimes combined with the mattifying powder called polymethylsilsesquioxane), a viscosity controlling or an opacifying (reduces the transparency of the formula) agent.
  17. 17A nice, multi-functional helper ingredient that's especially useful in sunscreens. It can solubilize some commonly used UV-filters like Oxybenzone or Avobenzone and it can also help to increase the SPF rating of sunscreens. It's also cosmetically el…
  18. 18An often used emollient with a light and silky feel. It's very mild to both skin and eyes and spreads nicely and easily. It's often used in sunscreens as it's also an excellent solvent for sunscreen agents.
  19. 19It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
  20. 20The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
Source · incidecoder.com
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Product index

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Comparison edit

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