Skin science article
PCA Skin ReBalance Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer
PCA Skin ReBalance Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier. This barrier-repair moisturizer is formulated around Niac
PCA Skin ReBalance Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer
This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier.
This barrier-repair moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ethylhexyl Isononanoate
Glycereth-26
Butylene Glycol
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Phenoxyethanol
Niacinamide
Carbomer
Polyisobutene
Caprylyl Glycol
Bisabolol
Sodium Hydroxide
Ethylhexylglycerin
Hexylene Glycol
PEG-7 Trimethylolpropane Coconut Ether
Tocopheryl Acetate
Oenothera Biennis Oil
Borago Officinalis Seed Oil
Aloe Barbadensis Leaf Juice
Sodium Hyaluronate
Water, Ethylhexyl Isononanoate, Glycereth-26, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Niacinamide, Carbomer, Polyisobutene, Caprylyl Glycol, Bisabolol, Sodium Hydroxide, Ethylhexylglycerin, Hexylene Glycol, PEG-7 Trimethylolpropane Coconut Ether, Tocopheryl Acetate, Oenothera Biennis Oil, Borago Officinalis Seed Oil, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate
Propanediol
Dicaprylyl Carbonate
Glycerin
Methylpropanediol
Cetearyl Alcohol
Stearyl Alcohol
Mangifera Indica Seed Butter
Acetyl Hexapeptide-1
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Acetyl Tetrapeptide-2
Acetyl Dipeptide-1 Cetyl Ester
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Carnosine
Ceramide NP
Ceramide AP
Ceramide EOP
Collagen
Serine
Alanine
Glycine
Glutamic Acid
Lysine Hcl
Threonine
Arginine
Proline
Hyaluronic Acid
Linoleic Acid
Linolenic Acid
Sodium PCA
Sodium Lactate
Panthenol
Tocopherol
Betaine
PCA
Cyanocobalamin
Xylitol
Anhydroxylitol
Xylitylglucoside
Sorbitan Olivate
Hydroxyethylcellulose
Xanthan Gum
Cetearyl Olivate
Sorbitan Laurate
Phytosphingosine
Cholesterol
Polysorbate 60
Hydroxyacetophenone
Glycine Soja Oil
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Polysorbate 20
Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Dimethicone
Sodium Phytate
Sodium Lauroyl Lactylate
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Leuconostoc/Radish Root Ferment Filtrate
Citric Acid
Parfum
Citral
Limonene
Linalool
Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Methylpropanediol, Cetearyl Alcohol, Stearyl Alcohol, Mangifera Indica Seed Butter, Niacinamide, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carnosine, Ceramide NP, Ceramide AP, Ceramide EOP, Collagen, Serine, Alanine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Hyaluronic Acid, Sodium Hyaluronate, Linoleic Acid, Linolenic Acid, Sodium PCA, Sodium Lactate, Panthenol, Tocopherol, Tocopheryl Acetate, Betaine, PCA, Cyanocobalamin, Xylitol, Anhydroxylitol, Xylitylglucoside, Sorbitan Olivate, Carbomer, Hydroxyethylcellulose, Xanthan Gum, Cetearyl Olivate, Sorbitan Laurate, Phytosphingosine, Cholesterol, Polysorbate 60, Butylene Glycol, Hydroxyacetophenone, Glycine Soja Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Dimethicone, Sodium Phytate, Sodium Lauroyl Lactylate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Parfum, Citral, Limonene, Linalool
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!