Peach & Lily Copper Peptide Pro Firming Serum Versus Naturium Multi-Peptide Advanced Serum

Peach & Lily Copper Peptide Pro Firming Serum Versus Naturium Multi-Peptide Advanced Serum

This anti-aging serum is formulated around Copper Tripeptide-1 and Acetyl Hexapeptide-8 to soften the look of wrinkles.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Dipropylene Glycol

Glycerin

1,2-Hexanediol

Betaine

Copper Tripeptide-1

Acetyl Hexapeptide-8

Palmitoyl Tripeptide-1

Tetrapeptide-21

Tetrapeptide-30

Heptasodium Hexacarboxymethyl Dipeptide-12

Acetyl Tetrapeptide-5

Palmitoyl Tripeptide-38

Palmitoyl Pentapeptide-4

Dipeptide-2

Tripeptide-1

Hexapeptide-9

Nonapeptide-1

Collagen Extract

Serine

Methionine

Cysteine

Arginine

Acmella Oleracea Extract

Alpha-Glucan Oligosaccharide

Sodium PCA

Ulmus Davidiana Root Extract

Cichorium Intybus Root Extract

Helianthus Tuberosus Root Extract

Tremella Fuciformis Extract

Fomes Officinalis Extract

Lentinus Edodes Extract

Pyrus Malus Fruit Extract

Lens Esculenta Fruit Extract

Citrullus Lanatus Fruit Extract

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Sodium Hyaluronate

Sodium Hyaluronate Crosspolymer

Potassium Hyaluronate

Squalane

Ficus Carica Fruit Extract

Cynanchum Atratum Extract

Hydroxypropyltrimonium Hyaluronate

Ocimum Sanctum Leaf Extract

Melia Azadirachta Leaf Extract

Curcuma Longa Root Extract

Corallina Officinalis Extract

Solanum Melongena Fruit Extract

Coccinia Indica Fruit Extract

Gellan Gum

Butylene Glycol

Adenosine

Aloe Barbadensis Flower Extract

Melia Azadirachta Flower Extract

Polyglyceryl-10 Eicosanedioate/Tetradecanedioate

Polyquaternium-51

Sodium Polyacryloyldimethyl Taurate

Hydroxypropyl Cyclodextrin

Ethylhexylglycerin

Hydroxyethylcellulose

Caprylyl Glycol

Water, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Tetrapeptide-21, Tetrapeptide-30, Heptasodium Hexacarboxymethyl Dipeptide-12, Acetyl Tetrapeptide-5, Palmitoyl Tripeptide-38, Palmitoyl Pentapeptide-4, Dipeptide-2, Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Collagen Extract, Serine, Methionine, Cysteine, Arginine, Acmella Oleracea Extract, Alpha-Glucan Oligosaccharide, Sodium PCA, Ulmus Davidiana Root Extract, Cichorium Intybus Root Extract, Helianthus Tuberosus Root Extract, Tremella Fuciformis Extract, Fomes Officinalis Extract, Lentinus Edodes Extract, Pyrus Malus Fruit Extract, Lens Esculenta Fruit Extract, Citrullus Lanatus Fruit Extract, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Squalane, Ficus Carica Fruit Extract, Cynanchum Atratum Extract, Hydroxypropyltrimonium Hyaluronate, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Solanum Melongena Fruit Extract, Coccinia Indica Fruit Extract, Gellan Gum, Butylene Glycol, Adenosine, Aloe Barbadensis Flower Extract, Melia Azadirachta Flower Extract, Polyglyceryl-10 Eicosanedioate/Tetradecanedioate, Polyquaternium-51, Sodium Polyacryloyldimethyl Taurate, Hydroxypropyl Cyclodextrin, Ethylhexylglycerin, Hydroxyethylcellulose, Caprylyl Glycol

Propanediol

Caprylic/Capric Triglyceride

Isopentyldiol

Ethylhexyl Polyhydroxystearate

Tetradecane

Glyceryl Stearate Citrate

Butyrospermum Parkii Butter

Polyglyceryl-3 Stearate

Helianthus Annuus Extract

Oryza Sativa Bran Extract

Mannitol

Phosphatidylcholine

Ferulic Acid

Copper Palmitoyl Heptapeptide-14

Palmitoyl Sh-Heptapeptide-12 Sp

Hydrolyzed Collagen

Rosmarinus Officinalis Leaf Extract

Lactic Acid/Glycolic Acid Copolymer

Tocopherol

Pullulan

Lysolecithin

Sclerotium Gum

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Dimethicone

Sodium Phytate

Diglycerin

Hydrogenated Lecithin

Silica

Cetyl Alcohol

Hydroxyacetophenone

Polysorbate 60

Sorbitan Isostearate

Sodium Hydroxide

Sodium Benzoate

Potassium Sorbate

Polyvinyl Alcohol

Decyl Glucoside

Xanthan Gum

Tocopheryl Acetate

Sodium Chloride

Citric Acid

Phenoxyethanol

Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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