Skin science article
Peach & Lily Glass Skin Refining Serum Versus Paula's Choice Defense Antioxidant Pore Purifier
Peach & Lily Glass Skin Refining Serum Versus Paula's Choice Defense Antioxidant Pore Purifier This smoothing serum is formulated around Niacinamide and Sodium Hyaluronate to refine skin texture and hydrate skin. This pore-care treatment is formulated around A
Peach & Lily Glass Skin Refining Serum Versus Paula's Choice Defense Antioxidant Pore Purifier
This smoothing serum is formulated around Niacinamide and Sodium Hyaluronate to refine skin texture and hydrate skin.
This pore-care treatment is formulated around Ascorbyl Glucoside and Salicylic Acid to refine the look of pores and balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Propanediol
Butylene Glycol
Niacinamide
1,2-Hexanediol
Prunus Persica Fruit Extract
Dioscorea Japonica Root Extract
Sodium Hyaluronate
Adenosine
Hydrolyzed Sodium Hyaluronate
Madecassoside
Hydrolyzed Hyaluronic Acid
Sodium Acetylated Hyaluronate
Acetyl Octapeptide-3
Ethylhexylglycerin
Hydrolyzed Corn Starch
Sodium Carbomer
Beta-Glucan
Saccharide Isomerate
Phytic Acid
Sucrose
Asiaticoside
Caprylyl Glycol
Water, Propanediol, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Prunus Persica Fruit Extract, Dioscorea Japonica Root Extract, Sodium Hyaluronate, Adenosine, Hydrolyzed Sodium Hyaluronate, Madecassoside, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Acetyl Octapeptide-3, Ethylhexylglycerin, Hydrolyzed Corn Starch, Sodium Carbomer, Beta-Glucan, Saccharide Isomerate, Phytic Acid, Sucrose, Asiaticoside, Caprylyl Glycol
Ethoxydiglycol
Glycerin
Ascorbyl Glucoside
Panthenol
Salicylic Acid
Camellia Sinensis Callus
Glycyrrhiza Glabra Root Extract
Potassium Azeloyl Diglycinate
Coffea Arabica Fruit Extract
Ceramide NP
Vitis Vinifera Seed Extract
Panax Ginseng Root Extract
Epigallocatechin Gallate
Ubiquinone
Calendula Officinalis Flower Extract
Lonicera Caprifolium Flower Extract
Lecithin
Centella Asiatica Extract
Sucrose Stearate
Glycine Soja Seed Extract
Hydrogenated Lecithin
Carbomer
Tetrasodium Glutamate Diacetate
Caprylic/Capric Triglyceride
Polysorbate 20
Polyglyceryl-10 Stearate
Hydroxyethylcellulose
Sodium Hydroxide
Phenoxyethanol
Water, Propanediol, Butylene Glycol, Ethoxydiglycol, Glycerin, Ascorbyl Glucoside, Panthenol, Salicylic Acid, Camellia Sinensis Callus, Glycyrrhiza Glabra Root Extract, Potassium Azeloyl Diglycinate, Coffea Arabica Fruit Extract, Ceramide NP, Vitis Vinifera Seed Extract, Panax Ginseng Root Extract, Niacinamide, Phytic Acid, Epigallocatechin Gallate, Adenosine, Ubiquinone, Calendula Officinalis Flower Extract, Lonicera Caprifolium Flower Extract, Sodium Hyaluronate, Lecithin, Centella Asiatica Extract, Sucrose Stearate, Glycine Soja Seed Extract, Hydrogenated Lecithin, Carbomer, Tetrasodium Glutamate Diacetate, Caprylic/Capric Triglyceride, Caprylyl Glycol, Polysorbate 20, Polyglyceryl-10 Stearate, Hydroxyethylcellulose, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Phytic Acid is a gentle AHA and antioxidant. AHAs are chemical exfoliants that help remove dead skin cells. Phytic Acid has a slight and mild exfoliating effect.
The chemical makeup makes it classified as an AHA, much like lactic acid.
In some cases, it is a chelating agent. Chelating agents help prevent metals from binding to water, helping to stabilize the ingredients in a product.
An interesting fact about phytic acid is that it is considered an antinutrient. People do not have the enzyme needed to properly breakdown and digest phytic acid. When ingested, phytic acid binds to minerals and prevents them from being absorbed.
Read more about some other popular AHA's here:
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!