Skin science article
Peach & Lily Peptide Pro Firming Moisturizer Versus Round Lab 1025 Dokdo Cream
Peach & Lily Peptide Pro Firming Moisturizer Versus Round Lab 1025 Dokdo Cream This anti-aging moisturizer is formulated around Collagen Extract and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin. This barrier-repair moisturizer is formul
Peach & Lily Peptide Pro Firming Moisturizer Versus Round Lab 1025 Dokdo Cream
This anti-aging moisturizer is formulated around Collagen Extract and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.
This barrier-repair moisturizer is formulated around Ceramide NP and Panthenol to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Sorbitol
Glycerin
Cetearyl Alcohol
Butylene Glycol Dicaprylate/Dicaprate
1,2-Hexanediol
Caprylic/Capric Triglyceride
Hydrogenated Polydecene
C10-18 Triglycerides
Stearic Acid
Cetearyl Glucoside
Collagen Extract
Acetyl Hexapeptide-8
Dipeptide-2
Acetyl Tetrapeptide-5
Sh-Oligopeptide-1
Copper Tripeptide-1
Tripeptide-1
Palmitoyl Tripeptide-5
Palmitoyl Tripeptide-1
Nonapeptide-1
Hexapeptide-9
Palmitoyl Pentapeptide-4
Sh-Polypeptide-1
Serine
Methionine
Cysteine
Arginine
Tremella Fuciformis Extract
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Polyglutamic Acid
Polyglyceryl-3 Methylglucose Distearate
Hydrolyzed Sodium Hyaluronate
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Squalane
Sodium Hyaluronate
Sodium Hyaluronate Crosspolymer
Glyceryl Glucoside
Saccharomyces/Rice Ferment Filtrate
Prunus Mume Fruit Extract
Curcuma Longa Root Extract
Corallina Officinalis Extract
Panax Ginseng Callus Culture Extract
Solanum Melongena Fruit Extract
Prunus Armeniaca Fruit Extract
Aloe Barbadensis Leaf Extract
Ocimum Sanctum Leaf Extract
Adenosine
Tocopherol
Sorbitan Stearate
Carbomer
Sodium Polyacryloyldimethyl Taurate
Origanum Majorana Leaf Extract
Melia Azadirachta Leaf Extract
Melia Azadirachta Flower Extract
Aloe Barbadensis Flower Extract
Phellinus Linteus Extract
3-O-Ethyl Ascorbic Acid
Glucose
Ethylhexylglycerin
Coccinia Indica Fruit Extract
Pentylene Glycol
Caprylyl Glycol
Tropolone
Citrus Aurantium Bergamia Fruit Oil
Water, Butylene Glycol, Sorbitol, Glycerin, Cetearyl Alcohol, Butylene Glycol Dicaprylate/Dicaprate, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Hydrogenated Polydecene, C10-18 Triglycerides, Stearic Acid, Cetearyl Glucoside, Collagen Extract, Acetyl Hexapeptide-8, Dipeptide-2, Acetyl Tetrapeptide-5, Sh-Oligopeptide-1, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Nonapeptide-1, Hexapeptide-9, Palmitoyl Pentapeptide-4, Sh-Polypeptide-1, Serine, Methionine, Cysteine, Arginine, Tremella Fuciformis Extract, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Polyglutamic Acid, Polyglyceryl-3 Methylglucose Distearate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Squalane, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Glyceryl Glucoside, Saccharomyces/Rice Ferment Filtrate, Prunus Mume Fruit Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Panax Ginseng Callus Culture Extract, Solanum Melongena Fruit Extract, Prunus Armeniaca Fruit Extract, Aloe Barbadensis Leaf Extract, Ocimum Sanctum Leaf Extract, Adenosine, Tocopherol, Sorbitan Stearate, Carbomer, Sodium Polyacryloyldimethyl Taurate, Origanum Majorana Leaf Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Aloe Barbadensis Flower Extract, Phellinus Linteus Extract, 3-O-Ethyl Ascorbic Acid, Glucose, Ethylhexylglycerin, Coccinia Indica Fruit Extract, Pentylene Glycol, Caprylyl Glycol, Tropolone, Citrus Aurantium Bergamia Fruit Oil
Dipropylene Glycol
Hydrogenated Poly(C6-14 Olefin)
Methyl Trimethicone
Caprylyl Methicone
Phenyl Trimethicone
C12-16 Alcohols
Butyrospermum Parkii Butter
Sea Water
Chondrus Crispus Extract
Saccharum Officinarum Extract
Glyceryl Stearate Se
Ceramide AP
Ceramide As
Ceramide EOP
Ceramide NP
Ceramide Ns
Polymethylsilsesquioxane
Palmitic Acid
Cetearyl Olivate
Sorbitan Olivate
Hydrogenated Lecithin
Copernicia Cerifera Wax
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Glyceryl Caprylate
Allantoin
Panthenol
Beta-Glucan
Cholesterol
Phytosphingosine
Disodium EDTA
Water, Glycerin, Caprylic/Capric Triglyceride, Dipropylene Glycol, Hydrogenated Poly(C6-14 Olefin), Cetearyl Alcohol, Methyl Trimethicone, 1,2-Hexanediol, Caprylyl Methicone, Phenyl Trimethicone, C12-16 Alcohols, Butyrospermum Parkii Butter, Sea Water, Chondrus Crispus Extract, Saccharum Officinarum Extract, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Glyceryl Stearate Se, Ceramide AP, Ceramide As, Ceramide EOP, Ceramide NP, Ceramide Ns, Polymethylsilsesquioxane, Palmitic Acid, Cetearyl Glucoside, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Lecithin, Copernicia Cerifera Wax, Stearic Acid, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ethylhexylglycerin, Glyceryl Caprylate, Allantoin, Panthenol, Butylene Glycol, Beta-Glucan, Cholesterol, Phytosphingosine, Disodium EDTA
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Cetearyl Glucoside is a sugar-based emulsifier. It is usually made by combining cetearyl alcohol and glucose.
Belonging to the aklyl polyglucoside (APG) family, Cetearyl Glucoside has a sugar "head" that loves water and a fatty "tail" that loves oil. This means it can shuffle oil and water into a stable and smooth emulsion.
Typical use levels are between 1-5% and this ingredient is considered to be non-irritating by the CIR Expert Panel Review.
Once applied, your skin's glucoside hydrolases breaks it down to the parent fatty alcohol and glucose. This is why this ingredient may not be fungal acne safe.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!