Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Peter Thomas Roth Oilless Oil 100% Purified Squalane Versus The INKEY List Squalane Oil

Peter Thomas Roth Oilless Oil 100% Purified Squalane Versus The INKEY List Squalane Oil This hydrating oil is formulated around Squalane to hydrate skin and strengthen the skin barrier. What's inside Benefits Ingredients Side-by-side Squalane Squalane 100% Rev

Peter Thomas Roth Oilless Oil 100% Purified Squalane Versus The INKEY List Squalane Oil

This hydrating oil is formulated around Squalane to hydrate skin and strengthen the skin barrier.

What's inside

Benefits

Ingredients Side-by-side

Squalane

Squalane 100%

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  7. 07Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  8. 08However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  9. 09Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  10. 10In skincare formulas, citric acid can:
  11. 11While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  12. 12Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  13. 13Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  14. 14However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  15. 15Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  16. 16Topically, glycerin does several things at once:
  17. 17Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  18. 18Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  19. 19This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  20. 20Just know very high concentrations (>40%) can feel tacky in low humidity.
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Retinol Serum

The Inkey List Retinol Serum The Inkey List Retinol Serum ingredients explained: Water (Aqua/Eau), Glycerin, Butylene Glycol, Propanediol, Dicaprylyl Carbonate, Dimethicone, Hydroxyethyl Ac…

Source: incidecoder.comView reference →

Product

The Inkey List PHA Body Water Cream

The Inkey List PHA Body Water Cream The Inkey List PHA Body Water Cream ingredients explained: Aqua (Water/Eau), C15-19 Alkane, Gluconolactone, Polyacrylate Crosspolymer-6, Phenoxyethanol, …

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side