Skin science article
Plated Skin Science Intense Serum Versus Is Clinical Super Serum Advance+
Plated Skin Science Intense Serum Versus Is Clinical Super Serum Advance+ This anti-aging serum is formulated around Panthenol and Hyaluronic Acid to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulated around Ascorb
Plated Skin Science Intense Serum Versus Is Clinical Super Serum Advance+
This anti-aging serum is formulated around Panthenol and Hyaluronic Acid to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Ascorbic Acid and Tripeptide-1 to soften the look of wrinkles and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Glycerin
Pentylene Glycol
Panthenol
Human Platelet Extract
Polyacrylate Crosspolymer-6
Hyaluronic Acid
Caprylyl Glycol
1,2-Hexanediol
Hydrolyzed Gelatin
Arginine
Silanetriol
Water, Glycerin, Pentylene Glycol, Panthenol, Human Platelet Extract, Polyacrylate Crosspolymer-6, Hyaluronic Acid, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Arginine, Silanetriol
Ascorbic Acid
Urea
Glucose
Tripeptide-1
Arbutin
Polyporus Umbellatus Extract
Calcium Pantothenate
Asiaticoside
Asiatic Acid
Zinc Sulfate
Phenoxyethanol
Water, Ascorbic Acid, Hyaluronic Acid, Pentylene Glycol, Urea, Glucose, Tripeptide-1, Arbutin, Polyporus Umbellatus Extract, Calcium Pantothenate, Asiaticoside, Asiatic Acid, Zinc Sulfate, Glycerin, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!