Plated Skin Science Intense Serum Versus MediCube PDRN Pink Collagen Exosome Shot

Plated Skin Science Intense Serum Versus MediCube PDRN Pink Collagen Exosome Shot

This anti-aging serum is formulated around Panthenol and Hyaluronic Acid to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Sodium DNA to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Pentylene Glycol

Panthenol

Human Platelet Extract

Polyacrylate Crosspolymer-6

Hyaluronic Acid

Caprylyl Glycol

1,2-Hexanediol

Hydrolyzed Gelatin

Arginine

Silanetriol

Water, Glycerin, Pentylene Glycol, Panthenol, Human Platelet Extract, Polyacrylate Crosspolymer-6, Hyaluronic Acid, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Arginine, Silanetriol

Butylene Glycol

Dipropylene Glycol

Niacinamide

Sodium Polyacrylate

Cetearyl Olivate

Phenyl Trimethicone

Sorbitan Olivate

Hydrolyzed Sponge

Glyceryl Acrylate/Acrylic Acid Copolymer

Ethylhexylglycerin

Calcium Aluminum Borosilicate

Adenosine

Disodium EDTA

Pvm/Ma Copolymer

Lactobacillus Extracellular Vesicles

Cyanocobalamin

Sodium DNA

Milk Exosomes

Collagen Extract

Macadamia Ternifolia Seed Oil

Caprylic/Capric Triglyceride

Alcohol

Hydrogenated Lecithin

Polysorbate 20

Retinol

Chondrus Crispus Extract

Cholesterol

Sodium Hyaluronate

Brassica Campestris Sterols

Polyglyceryl-10 Laurate

Ceteth-3

Ceteth-5

Tocopheryl Acetate

Hydrolyzed Elastin

Potassium Cetyl Phosphate

Hydroxypropyltrimonium Hyaluronate

Acetyl Tetrapeptide-5

Palmitoyl Pentapeptide-4

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Palmitoyl Tripeptide-5

Sodium Hyaluronate Crosspolymer

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Water, Butylene Glycol, Dipropylene Glycol, Glycerin, Niacinamide, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Cetearyl Olivate, Phenyl Trimethicone, Sorbitan Olivate, Hydrolyzed Sponge, Glyceryl Acrylate/Acrylic Acid Copolymer, Ethylhexylglycerin, Calcium Aluminum Borosilicate, Adenosine, Disodium EDTA, Pvm/Ma Copolymer, Panthenol, Lactobacillus Extracellular Vesicles, Cyanocobalamin, Sodium DNA, Milk Exosomes, Collagen Extract, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Alcohol, Hydrogenated Lecithin, Polysorbate 20, Retinol, Chondrus Crispus Extract, Cholesterol, Sodium Hyaluronate, Brassica Campestris Sterols, Polyglyceryl-10 Laurate, Ceteth-3, Ceteth-5, Tocopheryl Acetate, Hydrolyzed Elastin, Potassium Cetyl Phosphate, Hydroxypropyltrimonium Hyaluronate, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Palmitoyl Tripeptide-5, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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