Skin science article
Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Versus Stratia Interface Cream
Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Versus Stratia Interface Cream This barrier-repair moisturizer is formulated around Ceramide NP and Hexapeptide-11 to strengthen the skin barrier and soften the look of wrinkles. This anti-aging moistu
Prequel Half & Half Peptides & Ceramides Fluid Moisturizer Versus Stratia Interface Cream
This barrier-repair moisturizer is formulated around Ceramide NP and Hexapeptide-11 to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Propanediol
Isopropyl Myristate
Ethylhexyl Olivate
Squalane
Hydrolyzed Rice Protein
Ceramide NP
Ceramide As
Ceramide Ns
Ceramide EOP
Ceramide AP
Hexapeptide-11
Matrixyl 3000
Polyglyceryl-10 Stearate
Triolein
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Glyceryl Oleate
Undecane
Hydroxyacetophenone
Glyceryl Dioleate
Caprylyl Glycol
Xanthan Gum
Tridecane
Betaine
Sodium Stearoyl Glutamate
Citric Acid
Sodium Phytate
Sodium PCA
Sodium Hydroxide
Sodium Lactate
PCA
Sodium Benzoate
Serine
Alanine
Palmitic Acid
Glycine
Hydrogenated Lecithin
Ethylhexyl Palmitate
Butylene Glycol
Phenoxyethanol
Ethylhexylglycerin
Glutamic Acid
Lysine Hcl
Threonine
Arginine
Proline
Tocopherol
Carbomer
Polysorbate 20
Water, Glycerin, Propanediol, Isopropyl Myristate, Ethylhexyl Olivate, Squalane, Hydrolyzed Rice Protein, Ceramide NP, Ceramide As, Ceramide Ns, Ceramide EOP, Ceramide AP, Hexapeptide-11, Matrixyl 3000, Polyglyceryl-10 Stearate, Triolein, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Oleate, Undecane, Hydroxyacetophenone, Glyceryl Dioleate, Caprylyl Glycol, Xanthan Gum, Tridecane, Betaine, Sodium Stearoyl Glutamate, Citric Acid, Sodium Phytate, Sodium PCA, Sodium Hydroxide, Sodium Lactate, PCA, Sodium Benzoate, Serine, Alanine, Palmitic Acid, Glycine, Hydrogenated Lecithin, Ethylhexyl Palmitate, Butylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Tocopherol, Carbomer, Polysorbate 20
Hydrogenated Polydecene
Panthenol
Ethoxydiglycol
Dimethicone
Rosa Canina Fruit Oil
Cetearyl Alcohol
Acetyl Glutamine
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Glycyrrhiza Glabra Root Extract
Allantoin
Sodium Hyaluronate
Glycolic Acid
Lactic Acid/Glycolic Acid Copolymer
Disodium EDTA
Polyacrylamide
Potassium Sorbate
C13-14 Isoparaffin
Polyvinyl Alcohol
Methylparaben
Propylparaben
Laureth-7
Diazolidinyl Urea
Water, Glycerin, Squalane, Hydrogenated Polydecene, Panthenol, Ethoxydiglycol, Dimethicone, Rosa Canina Fruit Oil, Cetearyl Alcohol, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Glycyrrhiza Glabra Root Extract, Allantoin, Caprylyl Glycol, Butylene Glycol, Sodium Hyaluronate, Glycolic Acid, Lactic Acid/Glycolic Acid Copolymer, Disodium EDTA, Polyacrylamide, Potassium Sorbate, Sodium Benzoate, C13-14 Isoparaffin, Polyvinyl Alcohol, Methylparaben, Propylparaben, Laureth-7, Diazolidinyl Urea, Xanthan Gum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.