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Skin science article

Prequel Multi-Quench Plumping Hydration Serum Versus Good Molecules Super Peptide Serum

Prequel Multi-Quench Plumping Hydration Serum Versus Good Molecules Super Peptide Serum This hydrating serum is formulated around Polyglutamic Acid and Ectoin to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Acetyl He

Prequel Multi-Quench Plumping Hydration Serum Versus Good Molecules Super Peptide Serum

This hydrating serum is formulated around Polyglutamic Acid and Ectoin to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Polyglutamic Acid

1,2-Hexanediol

Ectoin

Hibiscus Esculentus Fruit Extract

Erythritol

Phenoxyethanol

Propanediol

Xanthan Gum

Caprylyl Glycol

Carbomer

Ethylhexylglycerin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tocopherol

Citric Acid

Sodium Hydroxide

Water, Glycerin, Butylene Glycol, Polyglutamic Acid, 1,2-Hexanediol, Ectoin, Hibiscus Esculentus Fruit Extract, Erythritol, Phenoxyethanol, Propanediol, Xanthan Gum, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Citric Acid, Sodium Hydroxide

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Diheptyl Succinate

Capryloyl Glycerin/Sebacic Acid Copolymer

Glycine

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Sodium Hyaluronate

Copper Tripeptide-1

Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Sodium Hyaluronate, Copper Tripeptide-1, Tocopherol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  10. 10Topically, glycerin does several things at once:
  11. 11Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  12. 12Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  13. 13This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  14. 14Just know very high concentrations (>40%) can feel tacky in low humidity.
  15. 15Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  16. 16Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
  17. 17In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
  18. 18Interestingly, the size of the molecule affects its behavior:
  19. 19Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
  20. 20Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
Source · skinsort.com
02

Product index

Related product references

Product

Good Molecules Super Peptide Serum

Good Molecules Super Peptide Serum Ingredients in Good Molecules Super Peptide Serum explained: benefits, concerns, and detailed analysis of 16 ingredients including Water, Propanediol, and…

Source: skinsort.comView reference →

Product

Doa Kozmetik Peptide Serum

Doa Kozmetik Peptide Serum Ingredients in Doa Kozmetik Peptide Serum explained: benefits, concerns, and detailed analysis of 28 ingredients including Water, Pentylene Glycol, and Isopentyld…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side