Skin science article
PSA SKIN Visible Improvement Peptides & Niacinamide Serum Versus Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum
PSA SKIN Visible Improvement Peptides & Niacinamide Serum Versus Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum This anti-aging serum is formulated around Niacinamide and Acetyl Glucosamine to soften the look of wrinkles and refine skin texture
PSA SKIN Visible Improvement Peptides & Niacinamide Serum Versus Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum
This anti-aging serum is formulated around Niacinamide and Acetyl Glucosamine to soften the look of wrinkles and refine skin texture.
This brightening serum is formulated around Tranexamic Acid and Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Niacinamide
Glycerin
Propanediol
Ethyl Macadamiate
Isodecyl Neopentanoate
Butylene Glycol
Polysorbate 20
C12-15 Alkyl Benzoate
Acetyl Glucosamine
Beta-Glucan
Saccharomyces/Xylinum/Black Tea Ferment
Pichia/Resveratrol Ferment Extract
Bisabolol
Panthenol
Tocopheryl Acetate
Allantoin
Ergothioneine
Laminaria Digitata Extract
Chlorella Vulgaris Extract
Oxidized Glutathione
Ubiquinone
Tocopherol
Dimethyl Sulfone
Sea Water
Dimethyl Isosorbide
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-38
Malic Acid
Sclerotium Gum
Xanthan Gum
Carbomer
Sodium Gluconate
Ethylhexylglycerin
Hydroxypropyl Cyclodextrin
Saccharide Isomerate
Hydroxyethylcellulose
Potassium Sorbate
Phenoxyethanol
Water, Niacinamide, Glycerin, Propanediol, Ethyl Macadamiate, Isodecyl Neopentanoate, Butylene Glycol, Polysorbate 20, C12-15 Alkyl Benzoate, Acetyl Glucosamine, Beta-Glucan, Saccharomyces/Xylinum/Black Tea Ferment, Pichia/Resveratrol Ferment Extract, Bisabolol, Panthenol, Tocopheryl Acetate, Allantoin, Ergothioneine, Laminaria Digitata Extract, Chlorella Vulgaris Extract, Oxidized Glutathione, Ubiquinone, Tocopherol, Dimethyl Sulfone, Sea Water, Dimethyl Isosorbide, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Malic Acid, Sclerotium Gum, Xanthan Gum, Carbomer, Sodium Gluconate, Ethylhexylglycerin, Hydroxypropyl Cyclodextrin, Saccharide Isomerate, Hydroxyethylcellulose, Potassium Sorbate, Phenoxyethanol
Caprylic/Capric Triglyceride
C13-15 Alkane
Tranexamic Acid
Alpha-Arbutin
Pentylene Glycol
Palmaria Palmata Extract
Hydrolyzed Pea
Asparagopsis Armata Extract
Ascophyllum Nodosum Extract
Glycyrrhiza Glabra Root Extract
Pancratium Maritimum Extract
Ganoderma Lucidum Extract
Lentinus Edodes Extract
Lactobacillus Ferment
Hydrolyzed Pea Protein
Diacetyl Boldine
Dipotassium Glycyrrhizate
Lactobacillus
Glucose
Arginine/Lysine Polypeptide
Pentapeptide-34 Trifluoroacetate
C14-22 Alcohols
Hydrogenated Starch Hydrolysate
Hydroxyacetophenone
Sorbitan Caprylate
1,2-Hexanediol
Caprylyl Glycol
C12-20 Alkyl Glucoside
Sodium Phytate
Sodium Chloride
Sodium Succinate
Sorbic Acid
Sodium Benzoate
Water, Caprylic/Capric Triglyceride, C13-15 Alkane, Tranexamic Acid, Glycerin, Alpha-Arbutin, Pentylene Glycol, Tocopheryl Acetate, Palmaria Palmata Extract, Hydrolyzed Pea, Asparagopsis Armata Extract, Ascophyllum Nodosum Extract, Glycyrrhiza Glabra Root Extract, Pancratium Maritimum Extract, Ganoderma Lucidum Extract, Lentinus Edodes Extract, Lactobacillus Ferment, Hydrolyzed Pea Protein, Diacetyl Boldine, Dipotassium Glycyrrhizate, Lactobacillus, Bisabolol, Panthenol, Tocopherol, Glucose, Arginine/Lysine Polypeptide, Pentapeptide-34 Trifluoroacetate, C14-22 Alcohols, Xanthan Gum, Hydrogenated Starch Hydrolysate, Hydroxyacetophenone, Sorbitan Caprylate, 1,2-Hexanediol, Caprylyl Glycol, C12-20 Alkyl Glucoside, Propanediol, Carbomer, Sodium Phytate, Butylene Glycol, Sodium Chloride, Sodium Succinate, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
You'll likely see use concentrations quite low, usually 0.1-0.2%.
Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.