Puca – Pure & Care EGF Peptide Serum Versus Puca – Pure & Care Collagen Serum

Puca – Pure & Care EGF Peptide Serum Versus Puca – Pure & Care Collagen Serum

This hydrating serum is formulated around Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Ingredients Side-by-side

Water

Propanediol

Corn Gluten Amino Acids

Glycerin

Butylene Glycol

Sodium Hyaluronate

Oligopeptide-1

Oligopeptide-2

Oligopeptide-5

Hyaluronic Acid

Collagen

Silk Extract

Avena Sativa Kernel Extract

Glycyrrhiza Glabra Root Extract

Portulaca Oleracea Extract

Camellia Sinensis Leaf Extract

Chamomilla Recutita Flower Extract

Rosmarinus Officinalis Leaf Extract

Scutellaria Baicalensis Root Extract

Centella Asiatica Extract

Polygonum Cuspidatum Root Extract

Beta-Glucan

Panthenol

Hexylene Glycol

Xanthan Gum

Phenoxyethanol

Hydroxyacetophenone

Ethylhexylglycerin

Potassium Sorbate

Sodium Hydroxide

Water, Propanediol, Corn Gluten Amino Acids, Glycerin, Butylene Glycol, Sodium Hyaluronate, Oligopeptide-1, Oligopeptide-2, Oligopeptide-5, Hyaluronic Acid, Collagen, Silk Extract, Avena Sativa Kernel Extract, Glycyrrhiza Glabra Root Extract, Portulaca Oleracea Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Scutellaria Baicalensis Root Extract, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Beta-Glucan, Panthenol, Hexylene Glycol, Xanthan Gum, Phenoxyethanol, Hydroxyacetophenone, Ethylhexylglycerin, Potassium Sorbate, Sodium Hydroxide

Hydrolyzed Collagen

Dipropylene Glycol

Morus Alba Root Extract

Sodium Polyacrylate

Glycosphingolipids

Euglena Gracilis Polysaccharide

Opuntia Ficus-Indica Extract

Water, Butylene Glycol, Hydrolyzed Collagen, Corn Gluten Amino Acids, Dipropylene Glycol, Phenoxyethanol, Sodium Hyaluronate, Morus Alba Root Extract, Sodium Polyacrylate, Silk Extract, Glycosphingolipids, Portulaca Oleracea Extract, Euglena Gracilis Polysaccharide, Glycerin, Potassium Sorbate, Hexylene Glycol, Propanediol, Beta-Glucan, Opuntia Ficus-Indica Extract, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.

It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.

On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin

The more interesting story is underneath:

Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.

A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.

It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.

This ingredient gets along with pretty much everything and is typically used around 0.1-1%.

Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

We don't have a description for Corn Gluten Amino Acids yet.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

This extract comes from Purslane, a succulent. It has anti-inflammatory, antioxidant, and hydrating properties.

Purslane is very nutritious. It contains omega-3 fatty acids, NMFs, many vitamins, minerals, and antioxidants. The vitamins found in purslane include: Vitamin C, Vitamin A, and Vitamin E.

Fun fact: Purslane is a succulent with an extensive habitat. It is used in traditional Korean medicine to treat irritated skin.

Nowadays, purslane is becoming a superfood due to its highly nutritious content.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

We don't have a description for Silk Extract yet.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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