Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

PURITO B5 Panthenol Re-Barrier Cream Versus Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free)

PURITO B5 Panthenol Re-Barrier Cream Versus Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free) This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Panthenol to strengthen the skin barrier and calm redness. This anti

PURITO B5 Panthenol Re-Barrier Cream Versus Olay Regenerist Collagen Peptide 24 Moisturizer (Fragrance Free)

This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Panthenol to strengthen the skin barrier and calm redness.

This anti-aging moisturizer is formulated around Niacinamide and Panthenol to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Centella Asiatica Extract

Panthenol 10%

Squalane

Butylene Glycol

Water

1,2-Hexanediol

Niacinamide

Hydrolyzed Jojoba Esters

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Hydroxyacetophenone

Tromethamine

Dipotassium Glycyrrhizate

Ethylhexylglycerin

Disodium EDTA

Xanthan Gum

Sodium Hyaluronate

Madecassoside

Asiaticoside

Asiatic Acid

Copper Tripeptide-1

Madecassic Acid

Centella Asiatica Extract, Panthenol 10%, Squalane, Butylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Hydrolyzed Jojoba Esters, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyacetophenone, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Xanthan Gum, Sodium Hyaluronate, Madecassoside, Asiaticoside, Asiatic Acid, Copper Tripeptide-1, Madecassic Acid

Glycerin

Isohexadecane

Dimethicone

Isopropyl Isostearate

Stearyl Alcohol

Polyacrylamide

Panthenol

Palmitoyl Pentapeptide-4

Tremella Fuciformis Sporocarp Extract

Tapioca Starch

C13-14 Isoparaffin

Caprylyl Glycol

Dimethiconol

Laureth-7

Cetearyl Alcohol

Cetearyl Glucoside

Palmitic Acid

Stearic Acid

Cetyl Alcohol

Behenyl Alcohol

PEG-100 Stearate

Titanium Dioxide

Polymethylsilsesquioxane

Phenoxyethanol

Water, Glycerin, Niacinamide, Isohexadecane, Dimethicone, Isopropyl Isostearate, Stearyl Alcohol, Polyacrylamide, Panthenol, Palmitoyl Pentapeptide-4, Tremella Fuciformis Sporocarp Extract, Tapioca Starch, C13-14 Isoparaffin, Caprylyl Glycol, Dimethiconol, Laureth-7, Cetearyl Alcohol, Cetearyl Glucoside, Palmitic Acid, Stearic Acid, Cetyl Alcohol, Behenyl Alcohol, Disodium EDTA, PEG-100 Stearate, Titanium Dioxide, Polymethylsilsesquioxane, 1,2-Hexanediol, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
  4. 04Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
  5. 05Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
  6. 06In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
  7. 07Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
  8. 08Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
  9. 09It plays several roles in a formula:
  10. 10Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
  11. 11Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
  12. 12However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
  13. 13Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
  14. 14Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
  15. 15Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
  16. 16This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
  17. 17A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
  18. 18Cetearyl Glucoside is a sugar-based emulsifier. It is usually made by combining cetearyl alcohol and glucose.
  19. 19Belonging to the aklyl polyglucoside (APG) family, Cetearyl Glucoside has a sugar "head" that loves water and a fatty "tail" that loves oil. This means it can shuffle oil and water into a stable and smooth emulsion.
  20. 20Typical use levels are between 1-5% and this ingredient is considered to be non-irritating by the CIR Expert Panel Review.
Source · skinsort.com
03

Comparison edit

Read side by side