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Skin science article

PURITO Centella Unscented Serum Versus The Ordinary Multi Peptides + Copper Peptide 1%

PURITO Centella Unscented Serum Versus The Ordinary Multi Peptides + Copper Peptide 1% This calming serum is formulated around Centella Asiatica Extract and Niacinamide to calm redness and strengthen the skin barrier. This anti-aging serum is formulated around

PURITO Centella Unscented Serum Versus The Ordinary Multi Peptides + Copper Peptide 1%

This calming serum is formulated around Centella Asiatica Extract and Niacinamide to calm redness and strengthen the skin barrier.

This anti-aging serum is formulated around Lactococcus Ferment Lysate and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Centella Asiatica Extract 49%

Water

Glycerin

Dipropylene Glycol

Niacinamide

Butylene Glycol

1,2-Hexanediol

Glycereth-26

Ceramide NP

Sodium Hyaluronate

Asiaticoside

Asiatic Acid

Madecassic Acid

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Dipeptide-10

Carbomer

Arginine

Sclerotium Gum

Hydrolyzed Jojoba Esters

Caprylyl Glycol

Polyglyceryl-10 Myristate

Panthenol

Polyglyceryl-10 Laurate

Hydrogenated Lecithin

Camellia Sinensis Leaf Extract

Pancratium Maritimum Extract

Dipotassium Glycyrrhizate

Disodium EDTA

Adenosine

Centella Asiatica Extract 49%, Water, Glycerin, Dipropylene Glycol, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Glycereth-26, Ceramide NP, Sodium Hyaluronate, Asiaticoside, Asiatic Acid, Madecassic Acid, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Dipeptide-10, Carbomer, Arginine, Sclerotium Gum, Hydrolyzed Jojoba Esters, Caprylyl Glycol, Polyglyceryl-10 Myristate, Panthenol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Camellia Sinensis Leaf Extract, Pancratium Maritimum Extract, Dipotassium Glycyrrhizate, Disodium EDTA, Adenosine

Lactococcus Ferment Lysate

Copper Tripeptide-1

Acetyl Hexapeptide-8

Pentapeptide-18

Palmitoyl Tripeptide-38

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetylarginyltryptophyl Diphenylglycine

Sodium Hyaluronate Crosspolymer

Allantoin

Glycine

Alanine

Serine

Valine

Isoleucine

Proline

Threonine

Histidine

Phenylalanine

Aspartic Acid

Trehalose

Fructose

Glucose

Maltose

Urea

Sodium PCA

PCA

Sodium Lactate

Citric Acid

Hydroxypropyl Cyclodextrin

Sodium Chloride

Sodium Hydroxide

Pentylene Glycol

Acacia Senegal Gum

Xanthan Gum

Polysorbate 20

Dimethyl Isosorbide

Sodium Benzoate

Ethylhexylglycerin

Phenoxyethanol

Chlorphenesin

Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Dicaprylyl Carbonate
  3. 03Cetearyl Isononanoate
  4. 04Glycerin
  5. 05Pentylene Glycol
  6. 06Cetearyl Alcohol
  7. 07Steareth-20
  8. 08Safflower Oil/Palm Oil Aminopropanediol Esters
  9. 09Laminaria Digitata Extract
  10. 10Opuntia Ficus-Indica Stem Extract
  11. 11Arabidopsis Thaliana Extract
  12. 12Marrubium Vulgare Meristem Cell Culture
  13. 13Leontopodium Alpinum Meristem Cell Culture
  14. 14Retinyl Palmitate
  15. 15Tocopheryl Acetate
  16. 16Tocopherol
  17. 17Micrococcus Lysate
  18. 18Caprylyl Glycol
  19. 19Hexylene Glycol
  20. 20Lactose
Source · skinsort.com
02

Product index

Related product references

Product

Nano Recipe Copper Peptide-1

Nano Recipe Copper Peptide-1 Ingredients in Nano Recipe Copper Peptide-1 explained: benefits, concerns, and detailed analysis of 4 ingredients including Copper Tripeptide-1, Water, and Prop…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side