Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

PURITO Deep Sea Droplet Serum Versus Mary & May 6 Peptide Complex Serum

PURITO Deep Sea Droplet Serum Versus Mary & May 6 Peptide Complex Serum This hydrating serum is formulated around Ectoin and Tremella Fuciformis Extract to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around Copper Tripepti

PURITO Deep Sea Droplet Serum Versus Mary & May 6 Peptide Complex Serum

This hydrating serum is formulated around Ectoin and Tremella Fuciformis Extract to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Copper Tripeptide-1 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Sea Water 66.01%

Butylene Glycol

Propanediol

Glycerin

Water

1,2-Hexanediol

Caprylic/Capric Triglyceride

Hydrolyzed Glycosaminoglycans

Betaine

Ectoin

Tremella Fuciformis Extract

Tremella Fuciformis Polysaccharide

Salicornia Herbacea Extract

Laminaria Japonica Extract

Caulerpa Lentillifera Extract

Acetyl Hexapeptide-8

Copper Tripeptide-1

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Xanthan Gum

Allantoin

Adenosine

Tromethamine

Disodium EDTA

Ethylhexylglycerin

Sea Water 66.01%, Butylene Glycol, Propanediol, Glycerin, Water, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Hydrolyzed Glycosaminoglycans, Betaine, Ectoin, Tremella Fuciformis Extract, Tremella Fuciformis Polysaccharide, Salicornia Herbacea Extract, Laminaria Japonica Extract, Caulerpa Lentillifera Extract, Acetyl Hexapeptide-8, Copper Tripeptide-1, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Allantoin, Adenosine, Tromethamine, Disodium EDTA, Ethylhexylglycerin

Glycereth-26

Arginine

Carbomer

Polyglyceryl-10 Laurate

Caprylyl Glycol

Hexapeptide-11

Hexapeptide-9

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Tripeptide-1

Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1, Hexapeptide-11, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Butylene Glycol
  4. 04Carbomer
  5. 05Polysorbate 20
  6. 06Palmitoyl Tripeptide-1
  7. 07Palmitoyl Tetrapeptide-7
  8. 08Aloe Barbadensis Leaf Extract
  9. 09Hyaluronic Acid
  10. 10Benzyl Alcohol
  11. 11Dehydroacetic Acid
  12. 12Water, Glycerin, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Aloe Barbadensis Leaf Extract, Hyaluronic Acid, Benzyl Alcohol, Dehydroacetic Acid
  13. 13Glycereth-26
  14. 141,2-Hexanediol
  15. 15Arginine
  16. 16Ethylhexylglycerin
  17. 17Polyglyceryl-10 Laurate
  18. 18Adenosine
  19. 19Caprylyl Glycol
  20. 20Copper Tripeptide-1
Source · skinsort.com
02

Product index

Related product references

Product

MARY & MAY 6 Peptide Complex Serum

MARY & MAY 6 Peptide Complex Serum MARY & MAY 6 Peptide Complex Serum ingredients explained: Purified Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Eth…

Source: incidecoder.comView reference →

Product

Mary & May 6 Peptide Complex Serum

Mary & May 6 Peptide Complex Serum Ingredients in Mary & May 6 Peptide Complex Serum explained: benefits, concerns, and detailed analysis of 17 ingredients including Water, Glycereth-26, an…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side