Skin science article
PURITO DermHA-3 Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster
PURITO DermHA-3 Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster This hydrating serum is formulated around Sodium Hyaluronate and Panthenol to hydrate skin and strengthen the skin barrier. What's inside Key Ingredients Benefits Concerns No concer
PURITO DermHA-3 Serum Versus Paula's Choice Pro-Collagen Multi-Peptide Booster
This hydrating serum is formulated around Sodium Hyaluronate and Panthenol to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Butylene Glycol
Sodium Hyaluronate
1,2-Hexanediol
Panthenol
Glycerin
Glyceryl Glucoside
Caprylyl Glycol
Pentylene Glycol
Hydroxyethylcellulose
Allantoin
Dipotassium Glycyrrhizate
Disodium EDTA
Malachite Extract
Copper Tripeptide-1
Hydrolyzed Hyaluronic Acid
Hydroxyacetophenone
Ethylhexylglycerin
Madecassoside
Asiaticoside
Asiatic Acid
Madecassic Acid
Sodium Acetylated Hyaluronate
Water, Butylene Glycol, Sodium Hyaluronate, 1,2-Hexanediol, Panthenol, Glycerin, Glyceryl Glucoside, Caprylyl Glycol, Pentylene Glycol, Hydroxyethylcellulose, Allantoin, Dipotassium Glycyrrhizate, Disodium EDTA, Malachite Extract, Copper Tripeptide-1, Hydrolyzed Hyaluronic Acid, Hydroxyacetophenone, Ethylhexylglycerin, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Sodium Acetylated Hyaluronate
Hydrolyzed Yeast Extract
Pyrus Malus Fruit Extract
Dimethicone
Propanediol
Ceramide AP
Palmitoyl Tetrapeptide-72 Amide
Sh-Polypeptide-121
Tridecapeptide-1
Polyglucuronic Acid
C9-12 Alkane
Ammonium Polyacryloyldimethyl Taurate
Polygonum Bistorta Root Extract
Bacillus Ferment
Lecithin
Sodium Phytate
Coco-Caprylate/Caprate
Hexylene Glycol
Cetyl Hydroxyethylcellulose
Xanthan Gum
Magnesium Chloride
Potassium Sorbate
Sodium Benzoate
Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Glucoside is made from glycerol and glucose.
It is a humectant. Humectants help hydrate your skin by drawing moisture to it from the air.
Some foods that contain glyceryl glucoside include sake, miso, and wines.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!