Skin science article
PURITO Dermide Cica Barrier Sleeping Pack Versus Paula's Choice Defense Nightly Reconditioning Moisturizer
PURITO Dermide Cica Barrier Sleeping Pack Versus Paula's Choice Defense Nightly Reconditioning Moisturizer This barrier-repair overnight mask is formulated around Centella Asiatica Extract and Madecassoside to strengthen the skin barrier and calm redness. This
PURITO Dermide Cica Barrier Sleeping Pack Versus Paula's Choice Defense Nightly Reconditioning Moisturizer
This barrier-repair overnight mask is formulated around Centella Asiatica Extract and Madecassoside to strengthen the skin barrier and calm redness.
This barrier-repair night moisturizer is formulated around Palmitoyl Hexapeptide-12 and Ceramide Ng to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Centella Asiatica Extract
Caprylic/Capric Triglyceride
Glycerin
Squalane
Simmondsia Chinensis Seed Oil
Cetearyl Alcohol
Potassium Cetyl Phosphate
Helianthus Annuus Seed Oil
Butylene Glycol
Polyglyceryl-3 Diisostearate
1,2-Hexanediol
Madecassoside
Asiaticoside
Madecassic Acid
Asiatic Acid
Panthenol
Ceramide NP
Sodium Hyaluronate
Hydroxyacetophenone
Sodium Carbomer
Hydrogenated Lecithin
Hydroxyethylcellulose
Camellia Sinensis Leaf Extract
Water, Centella Asiatica Extract, Caprylic/Capric Triglyceride, Glycerin, Squalane, Simmondsia Chinensis Seed Oil, Cetearyl Alcohol, Potassium Cetyl Phosphate, Helianthus Annuus Seed Oil, Butylene Glycol, Polyglyceryl-3 Diisostearate, 1,2-Hexanediol, Madecassoside, Asiaticoside, Madecassic Acid, Asiatic Acid, Panthenol, Ceramide NP, Sodium Hyaluronate, Hydroxyacetophenone, Sodium Carbomer, Hydrogenated Lecithin, Hydroxyethylcellulose, Camellia Sinensis Leaf Extract
Ethylhexyl Palmitate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Isoamyl Laurate
Prunus Serotina Fruit Extract
Almond/Borage/Linseed/Olive Acids/Glycerides
Medicago Sativa Extract
Sesamum Indicum Seed
Hydrolyzed Eruca Sativa Leaf
Sclerocarya Birrea Seed Oil
Hydrolyzed Algae Extract
Palmitoyl Hexapeptide-12
Palmitoyl Dipeptide-10
Ceramide Ng
Cocoyl Proline
Tocopherol
Allantoin
Trehalose
Eclipta Prostrata Extract
Potassium Azeloyl Diglycinate
Opuntia Ficus-Indica Stem Extract
Melia Azadirachta Leaf Extract
Leuconostoc/Radish Root Ferment Filtrate
Moringa Oleifera Seed Oil
Alaria Esculenta Extract
Adenosine Phosphate
PEG-10 Phytosterol
Tribehenin
Hydrolyzed Vegetable Protein
Sorbitan Olivate
Sodium Gluconate
Zinc Gluconate
Copper Gluconate
Magnesium Aspartate
Cetearyl Olivate
Isoamyl Cocoate
Polyglyceryl-10 Caprylate/Caprate
Microcrystalline Cellulose
C12-15 Alkyl Benzoate
Xanthan Gum
Pentylene Glycol
Butylene Glycol Stearate
Phenoxyethanol
Potassium Sorbate
Ethylhexylglycerin
Water, Glycerin, Ethylhexyl Palmitate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isoamyl Laurate, Prunus Serotina Fruit Extract, Almond/Borage/Linseed/Olive Acids/Glycerides, Medicago Sativa Extract, Sesamum Indicum Seed, Hydrolyzed Eruca Sativa Leaf, Sclerocarya Birrea Seed Oil, Hydrolyzed Algae Extract, Palmitoyl Hexapeptide-12, Palmitoyl Dipeptide-10, Sodium Hyaluronate, Ceramide Ng, Helianthus Annuus Seed Oil, Cocoyl Proline, Tocopherol, Allantoin, Trehalose, Eclipta Prostrata Extract, Potassium Azeloyl Diglycinate, Opuntia Ficus-Indica Stem Extract, Melia Azadirachta Leaf Extract, Leuconostoc/Radish Root Ferment Filtrate, Moringa Oleifera Seed Oil, Alaria Esculenta Extract, Adenosine Phosphate, PEG-10 Phytosterol, Tribehenin, Hydrolyzed Vegetable Protein, Sorbitan Olivate, Sodium Gluconate, Zinc Gluconate, Copper Gluconate, Magnesium Aspartate, Cetearyl Olivate, Isoamyl Cocoate, Caprylic/Capric Triglyceride, Polyglyceryl-10 Caprylate/Caprate, Microcrystalline Cellulose, C12-15 Alkyl Benzoate, Xanthan Gum, Pentylene Glycol, Butylene Glycol Stearate, Phenoxyethanol, Potassium Sorbate, Ethylhexylglycerin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!