Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Revolution Beauty Copper Peptide Serum Versus Youth To The People Triple Peptide + Cactus Oasis Serum

Revolution Beauty Copper Peptide Serum Versus Youth To The People Triple Peptide + Cactus Oasis Serum This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refin

Revolution Beauty Copper Peptide Serum Versus Youth To The People Triple Peptide + Cactus Oasis Serum

This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Opuntia Ficus-Indica Stem Extract and Palmitoyl Tripeptide-1 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Butylene Glycol

Xanthan Gum

Sodium Benzoate

Potassium Sorbate

Disodium EDTA

Carbomer

Polysorbate 20

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Caprylyl Glycol

Bis(Tripeptide-1) Copper Acetate

Ethylhexylglycerin

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Water, Propanediol, Glycerin, Butylene Glycol, Xanthan Gum, Sodium Benzoate, Potassium Sorbate, Disodium EDTA, Carbomer, Polysorbate 20, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Caprylyl Glycol, Bis(Tripeptide-1) Copper Acetate, Ethylhexylglycerin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

Pentylene Glycol

Opuntia Ficus-Indica Stem Extract

Palmitoyl Tripeptide-28

Sodium Hyaluronate

Hydrolyzed Sodium Hyaluronate

Sodium Hyaluronate Crosspolymer

Sodium Acetylated Hyaluronate

Synthetic Sapphire

Citrullus Lanatus Fruit Extract

Lens Esculenta Fruit Extract

Pyrus Malus Fruit Extract

Nephelium Lappaceum Peel Extract

Sodium PCA

Glutathione

Malachite Extract

Citric Acid

Hydroxypropyl Methylcellulose

Tetrasodium Glutamate Diacetate

Polyglutamic Acid

1,2-Hexanediol

Sodium Lactate

Hydroxyethylcellulose

Phenoxyethanol

Water, Butylene Glycol, Glycerin, Pentylene Glycol, Opuntia Ficus-Indica Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-28, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Synthetic Sapphire, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Nephelium Lappaceum Peel Extract, Sodium PCA, Glutathione, Malachite Extract, Citric Acid, Hydroxypropyl Methylcellulose, Tetrasodium Glutamate Diacetate, Polyglutamic Acid, 1,2-Hexanediol, Caprylyl Glycol, Sodium Lactate, Carbomer, Propanediol, Polysorbate 20, Hydroxyethylcellulose, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Caprylic/Capric Triglyceride
  4. 04Butyrospermum Parkii Butter
  5. 05Behenyl Alcohol
  6. 06Xylitylglucoside
  7. 07Niacinamide
  8. 08Squalane
  9. 09Sodium Acrylates Copolymer
  10. 10Acetyl Tetrapeptide-2
  11. 11Palmitoyl Heptapeptide-27
  12. 12Palmitoyl Oligopeptide-78
  13. 13Palmitoyl Octapeptide-24
  14. 14Phenoxyethanol
  15. 15Anhydroxylitol
  16. 161,2-Hexanediol
  17. 17Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  18. 18Xylitol
  19. 19Lecithin
  20. 20Ethylhexylglycerin
Source · skinsort.com
02

Product index

Related product references

Product

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Beyoutiful Copper Peptide Serum Beyoutiful Copper Peptide Serum ingredients explained: Dimethicone Crosspolymer-3, Cyclopentasiloxane, Squalane, Simmondsia Chinensis Seed Oil, Tocopheryl Ac…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side