Skin science article
Rodan + Fields Total Rf Serum Versus Boost Lab Multi-Peptide Anti-Ageing Serum
Rodan + Fields Total Rf Serum Versus Boost Lab Multi-Peptide Anti-Ageing Serum This anti-aging serum is formulated around Niacinamide and Asiaticoside to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulated around Di
Rodan + Fields Total Rf Serum Versus Boost Lab Multi-Peptide Anti-Ageing Serum
This anti-aging serum is formulated around Niacinamide and Asiaticoside to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Dimethicone
Isononyl Isononanoate
Glycerin
Niacinamide
Squalane
Isostearyl Alcohol
Glyceryl Linoleate
Butylene Glycol Cocoate
Asiaticoside
Pterocarpus Marsupium Bark Extract
Adenosine
Sodium Acetylated Hyaluronate
Tetrapeptide-16
Arginine PCA
Rosmarinic Acid
Rutin
Xymenynic Acid
Oligopeptide-10
Glyceryl Linolenate
Caprooyl Phytosphingosine
Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate
Honey Extract
Boswellia Serrata Extract
Panthenol
Pullulan
Ethylhexyl Cyclohexyl Urea
Hydroxyapatite
Oryza Sativa Bran Extract
Parfum
Cetyl Alcohol
Glyceryl Stearate
PEG-75 Stearate
Ceteth-20
Steareth-20
Sclerotium Gum
Lecithin
Ethylcellulose
Silica
Xanthan Gum
Tocopherol
Disodium EDTA
Caprylyl Glycol
Butylene Glycol
Hexylene Glycol
Pentylene Glycol
Phenoxyethanol
Potassium Sorbate
Sodium Benzoate
Mica
Tin Oxide
CI 77891
CI 77491
Water, Dimethicone, Isononyl Isononanoate, Glycerin, Niacinamide, Squalane, Isostearyl Alcohol, Glyceryl Linoleate, Butylene Glycol Cocoate, Asiaticoside, Pterocarpus Marsupium Bark Extract, Adenosine, Sodium Acetylated Hyaluronate, Tetrapeptide-16, Arginine PCA, Rosmarinic Acid, Rutin, Xymenynic Acid, Oligopeptide-10, Glyceryl Linolenate, Caprooyl Phytosphingosine, Methyl Carboxymethylphenyl Aminocarboxypropylphosphonate, Honey Extract, Boswellia Serrata Extract, Panthenol, Pullulan, Ethylhexyl Cyclohexyl Urea, Hydroxyapatite, Oryza Sativa Bran Extract, Parfum, Cetyl Alcohol, Glyceryl Stearate, PEG-75 Stearate, Ceteth-20, Steareth-20, Sclerotium Gum, Lecithin, Ethylcellulose, Silica, Xanthan Gum, Tocopherol, Disodium EDTA, Caprylyl Glycol, Butylene Glycol, Hexylene Glycol, Pentylene Glycol, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Mica, Tin Oxide, CI 77891, CI 77491
Xylitylglucoside
Anhydroxylitol
Xylitol
Acacia Senegal Gum
Biosaccharide Gum-4
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Acetyl Hexapeptide-8
1,2-Hexanediol
PEG-12 Dimethicone
Trisodium Ethylenediamine Disuccinate
Citric Acid
Ethylhexylglycerin
Water, Pentylene Glycol, Xylitylglucoside, Glycerin, Anhydroxylitol, Xylitol, Acacia Senegal Gum, Xanthan Gum, Biosaccharide Gum-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8, 1,2-Hexanediol, Caprylyl Glycol, PEG-12 Dimethicone, Trisodium Ethylenediamine Disuccinate, Citric Acid, Phenoxyethanol, Ethylhexylglycerin
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.