Skin science article
Sanitas Peptiderm Moisturizing Cream Versus Skinfix Barrier+ Triple Lipid-Peptide Cream
Sanitas Peptiderm Moisturizing Cream Versus Skinfix Barrier+ Triple Lipid-Peptide Cream This anti-aging moisturizer is formulated around Tetrahexyldecyl Ascorbate and Acetyl Octapeptide-3 to soften the look of wrinkles. This barrier-repair moisturizer is formu
Sanitas Peptiderm Moisturizing Cream Versus Skinfix Barrier+ Triple Lipid-Peptide Cream
This anti-aging moisturizer is formulated around Tetrahexyldecyl Ascorbate and Acetyl Octapeptide-3 to soften the look of wrinkles.
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
C12-15 Alkyl Benzoate
Simmondsia Chinensis Seed Oil
Carthamus Tinctorius Oleosomes
Tetrahexyldecyl Ascorbate
Tocopheryl Acetate
Hordeum Distichon Extract
Polyacrylate-13
Butylene Glycol
Acetyl Octapeptide-3
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-5
Palmitoyl Tetrapeptide-7
Pentapeptide-18
Sodium Hyaluronate
Glycosphingolipids
Perfluorodecalin
Phospholipids
Beta-Glucan
Santalum Album Extract
Avena Sativa Kernel Extract
Phellodendron Amurense Bark Extract
Inulin Lauryl Carbamate
Sucrose Palmitate
Polysorbate 20
Polyisobutene
Xanthan Gum
Carbomer
Caprylyl Glycol
Ethylhexylglycerin
Methylpropanediol
Caprylhydroxamic Acid
Water, Glycerin, C12-15 Alkyl Benzoate, Simmondsia Chinensis Seed Oil, Carthamus Tinctorius Oleosomes, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate, Hordeum Distichon Extract, Polyacrylate-13, Butylene Glycol, Acetyl Octapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Pentapeptide-18, Sodium Hyaluronate, Glycosphingolipids, Perfluorodecalin, Phospholipids, Beta-Glucan, Santalum Album Extract, Avena Sativa Kernel Extract, Phellodendron Amurense Bark Extract, Inulin Lauryl Carbamate, Sucrose Palmitate, Polysorbate 20, Polyisobutene, Xanthan Gum, Carbomer, Caprylyl Glycol, Ethylhexylglycerin, Methylpropanediol, Caprylhydroxamic Acid
Caprylic/Capric Triglyceride
Butyrospermum Parkii Butter
Olus Oil
Cetyl Lactate
Propanediol
C12-16 Alcohols
Caprylyl Caprylate/Caprate
Jojoba Oil/Macadamia Seed Oil Esters
Glyceryl Stearate Citrate
Palmitic Acid
Hydrogenated Lecithin
Oryza Sativa Bran Extract
Dilinoleic Acid/Propanediol Copolymer
Squalene
Ophiopogon Japonicus Root Extract
Phytosteryl Sunflowerseedate
Glycine Soja Extract
Pentylene Glycol
Ceramide NP
Ceramide AP
Ceramide EOP
Hydrolyzed Rice Protein
Chondrus Crispus Extract
Hydrogenated Vegetable Glycerides
Helianthus Annuus Extract
Citric Acid
Phytosteryl Macadamiate
Tocopherol
Rosmarinus Officinalis Leaf Extract
Aloe Barbadensis Leaf Juice
Trisodium Ethylenediamine Disuccinate
Phytosterols
Sodium Lauroyl Lactylate
Gluconolactone
Phenethyl Alcohol
Phytosphingosine
Cholesterol
Potassium Sorbate
Sodium Benzoate
Phenoxyethanol
Water, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.